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Research

Undiagnosed Diseases Network International (UDNI): White paper for global actions to meet patient needs

This white paper discusses the global progress in understanding novel diseases with the aim of encouraging more collaboration between international...

Research

Neighbourhood characteristics and the rate of identification of young people at ultra-high risk for psychosis

This study aimed to determine if the rate of identification of young people at ultra-high risk for psychosis was associated with the level of social deprivation

Research

Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children

Identified an association between polymorphisms in a long intergenic non-coding RNA (lincRNA) gene (AC011288.2) and pneumococcal bacteremia

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Older maternal age is associated with depression, anxiety, and stress symptoms in young adult female offspring

Older maternal age is associated with depression, anxiety, and stress symptoms in young adult females

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Maternal first trimester serum levels of free-beta human chorionic gonadotrophin and male genital anomalies

First trimester maternal levels of serum free-beta hCG are not associated with hypospadias or undescended testis

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Exploring the dynamics of respiratory syncytial virus (RSV) transmission in children

We develop a compartmental model for RSV infection, driven by a seasonal forcing function, and conduct parameter space and bifurcation analyses to document...

Research

Transcriptome analysis of recurrently deregulated genes across multiple cancers identifies new pan-cancer biomarkers

Genomewide expression profiling approach identified a comprehensive set of candidate biomarkers with pan-cancer potential

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Airway epithelial repair in health and disease: Orchestrator or simply a player?

This review attempts to highlight migration-specific and cell-extracellular matrix (ECM) aspects of repair used by epithelial cells

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A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology

Discover and replicate a locus indexed by rs77728904 at 9p21.3 associated with BCP-ALL susceptibility

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Mucin agarose gel electrophoresis: Western blotting for high-molecularweight glycoproteins

Conventional methods to separate mucin macromolecules by electrophoresis using an agarose gel and transfer protein into nitrocellulose membrane