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Association of prenatal alcohol exposure with offspring DNA methylation in mammals: a systematic review of the evidencePrenatal alcohol exposure is associated with a range of adverse offspring neurodevelopmental outcomes. Several studies suggest that PAE modifies DNA methylation in offspring cells and tissues, providing evidence for a potential mechanistic link to Fetal Alcohol Spectrum Disorder.
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A Genome-wide Association Study Identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1, and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis in BrazilOur goal was to identify genetic risk factors for cutaneous leishmaniasis (CL) caused by Leishmania braziliensis.
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Prospective surveillance of primary healthcare presentations for scabies and bacterial skin infections in Fiji, 2018-2019Scabies, impetigo, and other skin and soft tissue infections (SSTIs) are highly prevalent in many tropical, low-middle income settings, but information regarding their burden of disease is scarce. We conducted surveillance of presentations of scabies and SSTIs, including impetigo, abscesses, cellulitis, and seāvere SSTI, to primary health facilities in Fiji.
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Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of damsWhile maternal high fat diet compromised litter survival, it also promoted somatic and lung growth (increased lung volume) in the offspring
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An urgent need for antimicrobial stewardship in Indigenous rural and remote primary health careWe write this perspective to raise awareness of antimicrobial resistance as an issue in Indigenous primary health care
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Impact of lung disease on respiratory impedance in young children with cystic fibrosisThe present study investigated whether lung function measured by forced oscillation technique would be impaired in the presence of infection,...
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Natural environments, nature relatedness and the ecological theater: connecting satellites and sequencing to shinrin-yokuMechanisms-including aerobiological and epigenetic-that might help explain some of the noted positive health outcomes
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A novel role for interleukin-1 receptor signaling in the developmental regulation of immune responses to endotoxinSuggests that IL-1R1 expression provides an additional level of Myd88-dependent signaling during this period of heighted susceptibility to infection.
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Maternal work hours in early to middle childhood link to later adolescent diet qualityPrevious studies on maternal work hours and child diet quality have reported conflicting findings possibly due to differences in study design, lack of a...
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Exposure to UV Wavelengths in Sunlight Suppresses Immunity. To What Extent is UV-induced Vitamin D3 the Mediator Responsible?In experimental models, both vitamin D3-dependent and vitamin D3-independent pathways have been implicated in the mechanisms of UVR-induced systemic...