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Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in childrenInterleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.
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Gender-specific differences in adipose distribution and adipocytokines influence adolescent nonalcoholic fatty liver diseaseNonalcoholic fatty liver disease (NAFLD) is a predominantly adult-diagnosed disorder. Knowledge regarding the epidemiology, phenotype, and metabolic risk...
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An unopposed proinflammatory response is beneficial for survival in the oldest old. Results of the Leiden 85-plus studyThe capacity to generate an efficient innate immune response is pivotal for survival.
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Sterile abscess formation associated with depot leuprorelin acetate therapy for central precocious pubertyWe describe a case of an 8 year old girl with central precocious puberty
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Wound healing genes and susceptibility to cutaneous leishmaniasis in BrazilLeishmania braziliensis causes cutaneous (CL) and mucosal (ML) leishmaniasis. In the mouse, Fli1 was identified as a gene influencing enhanced wound healing...
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Perspectives on hand function in girls and women with Rett syndromeHand function is particularly affected and we discuss theoretical and practical perspectives for optimising hand function in Rett syndrome.
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Early mental health morbidity and later smoking at age 17 yearsWe examined the relationship between the onset and pattern of childhood mental health disorders and subsequent current smoking status at age 17 years.
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Viral infections and atopy in asthma pathogenesis: New rationales for asthma prevention and treatmentProspective birth cohort studies tracking asthma initiation and consolidation in community cohorts have identified viral infections occurring against a...
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Participation in population-based case-control studies: Does the observed decline vary by socio-economic status?An Australian study of childhood leukaemia (Aus-ALL) previously reported that control participation was positively associated with socio-economic status...
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Toll-like receptor 7 and 8 polymorphisms: Associations with functional effects and cellular and antibody responses to measles virus and vaccineThe functionality and effects of TLR7 and TLR8 polymorphisms on cellular and antibody responses was investigated after the first measles vaccine dose.