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Showing results for "lung disease preterm"

Research

Lung volume and ventilation inhomogeneity in preterm infants at 15-18 months corrected age

To assess whether lung volume and ventilation inhomogeneity in preterm infants at 15-18 months corrected age

Research

Preterm Paediatric Inhaled Corticosteroids Intervention (PICSI)

Understanding if ongoing inflammation in the lungs contributes to the poor lung health experienced by some children who were born preterm.

Research

Lung abnormalities do not influence aerobic capacity in school children born preterm

Children born preterm have impaired lung function and altered lung structure. However, there are conflicting reports on how preterm birth impacts aerobic exercise capacity in childhood. We aimed to investigate how neonatal history and a diagnosis of bronchopulmonary dysplasia (BPD) impact the relationship between function and structure of the lung, and aerobic capacity in school-aged children born very preterm.

Research

The impact of respiratory viruses on lung health after preterm birth

The aim of this review is to highlight the risk factors that may contribute to increased susceptibility to viral respiratory infections among preterm infants

Research

Oscillometry and spirometry are not interchangeable when assessing the bronchodilator response in children and young adults born preterm

The European Respiratory Society Oscillometry Taskforce identified that clinical correlates of bronchodilator responses are needed to advance oscillometry in clinical practice. The understanding of bronchodilator-induced oscillometry changes in preterm lung disease is poor. Here we describe a comparison of bronchodilator assessments performed using oscillometry and spirometry in a population born very preterm and explore the relationship between bronchodilator-induced changes in respiratory function and clinical outcomes.

News & Events

Limiting long term lung damage in preterm babies

With premature babies facing lung problems, researchers with the Children’s Lung Health group are working to identify ways to improve the long-term impact.

Research

Elevated leukotriene B4 and 8-isoprostane in exhaled breath condensate from preterm-born infants

Inflammation and oxidative stress play a key role in the development of bronchopulmonary dysplasia (BPD), possibly contributing to persistent respiratory morbidity after preterm birth. We aimed to assess if inflammatory markers were elevated in exhaled breath condensate (EBC) of infants born very prematurely (< 32 weeks gestation) at 12-16 corrected months of age, and if increased levels were associated with BPD diagnosis and respiratory morbidity.

Research

Ventilatory response and stability of oxygen saturation during a hypoxic challenge in very preterm infants

Preterm infants have immature control of breathing and impaired pulmonary gas exchange. We hypothesized that infants with bronchopulmonary dysplasia (BPD) have a blunted ventilatory response and peripheral oxygen saturation (SpO2 ) instability during a hypoxic challenge.

Exhaled breath condensate from healthy infants

Our researchers want to know what causes chronic lung disease in babies born very preterm. We can learn more about what's happening in the lungs by measuring the air that babies breathe out.