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Research

Immunosuppressive mechanisms of oncofetal reprogramming in the tumor microenvironment: implications in immunotherapy response

Both fetal and tumor tissue microenvironments display immunosuppressive features characterized by the presence of specific immunomodulatory stromal and immune cell populations. Recently, we discovered shared microenvironments between hepatocellular carcinoma and fetal tissues and described this phenomenon as an oncofetal ecosystem.

Research

The non-specific effects of maternal immunization on birth outcomes: The evidence, mechanisms, and the implications

Preterm birth (PTB) and stillbirth remain two of the most important causes of death, morbidity, and disability in childhood. Despite efforts to reduce PTB and stillbirth worldwide, rates of these adverse outcomes remain persistently elevated, independent of income setting. There is an urgent need for more effective interventions to reduce associated neonatal and early childhood morbidity and mortality.

Research

Birth outcomes and academic achievement in childhood: A population record linkage study

This study used population-based record linkage to examine the association between early life risk factors and academic achievement.

Research

Breastfeeding and early child development: A prospective cohort study

Breastfeeding has been associated with multiple developmental advantages for the infant; however, there have also been a number of studies that find...

News & Events

Bobbie brings baby’s brain to life

A lovable blue creature by the name of Bobbie has won the hearts and minds of Western Australians.

News & Events

First words: identifying risks to language development

Daniel Christensen, The Kids Research Institute Australia Life Course Centre research fellow, explained there was rapid change in a child’s brain in the first few years of life, making their home environment and relationship with carers incredibly important.

News & Events

Grandparent education linked to grandkids’ NAPLAN results

The effects of educational advantage or disadvantage get handed down through the generations according to a new study by researchers at the The Kids.

News & Events

Data reveals important clues about child abuse and neglect

Researchers working on the Developmental Pathways Project are determined to find out what makes families vulnerable to child abuse and neglect.

News & Events

Australian researchers join international project to curb unhealthy lifetime trajectories

Australian researchers join global effort to better understand how events during pregnancy and childhood influence the development of disease later in life.

News & Events

International expert to bring together WA leaders to improve outcomes for kids

Dr Jack Shonkoff, from Harvard University is visiting Perth this week as a guest of CoLab, Goodstart Early Learning and Child Australia.