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The airway epithelium in asthma displays altered repair and incomplete barrier formation.

The aim of this study was to determine whether assessment of early CT scan-detected bronchiectasis in young children with cystic fibrosis (CF) depends on...

Clinical trials for the treatment of cystic fibrosis (CF) lung disease are important to test and optimise new therapeutic interventions.

To examine the distribution of early structural lung changes in clinically stable infants and young children with cystic fibrosis using chest computed...

Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality.

Cross-sectional studies implicate neutrophilic inflammation and pulmonary infection as risk factors for early structural lung disease in infants and young...

The anti-inflammatory peptide, adrenomedullin (AM), and its cognate receptor are expressed in lung tissue, but its pathophysiological significance in airway...

Here we review the current knowledge of key molecular pathways that are dysregulated during persistent goblet cell differentiation

This study demonstrates novel intrinsic differences in tight junctions gene and protein expression between airway epithelial cells of children with and without asthma

Apically located tight junctions in airway epithelium perform a fundamental role in controlling macromolecule migration through paracellular spaces.