Search

Malt1 deficient mice develop an osteoporotic phenotype with increased osteoclastogenesis in vivo, but suggest that this is caused by inflammation

Chile has been hard hit by COVID-19, at times reporting around 6500 new cases a day, with many of these located in the capital Santiago.

Baseline signatures might contribute to identifying interventional targets to be modulated prior to vaccination in order to improve vaccination responses

The textbook view of vaccination is that it functions to induce immune memory of the specific pathogen components of the vaccine, leading to a quantitatively and qualitatively better response if the host is exposed to infection with the same pathogen

We describe here the effects of treatment with interferon-α2b in a cohort of confirmed COVID-19 cases in Wuhan, China

Protection may be further improved by integrating these approaches, namely vaccinating the neonate under the cover of vertically transferred maternal immunity

Implementation of lifelong ART of all HIV-infected women has the potential to improve maternal determinants of protective immunity in the young infant

Immunity is distinct in early life and greater precision is required in our understanding of mechanisms of early life protection to inform development of new pediatric vaccines

Systems biology and innovative data integration can provide fresh insights into the molecular ontogeny of the first week of life

Accumulating evidence indicates that an early, robust type 1 interferon (IFN) response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an inadequate IFN response associated with disease severity. Our objective was to examine the prophylactic potential of IFN administration to limit viral transmission.