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Showing results for "early lung health"

Research

Defective cell migration as a mechanism of dysregulated asthmatic airway repair

Anthony Stephen Kicic Stick A SM BSc (Hons) PhD MB BChir PhD MRCP FRACP Rothwell Family Fellow; Head, Airway Epithelial Research Head, P4 Respiratory

Research

Macrophage PD-1 associates with neutrophilia and reduced bacterial killing in early cystic fibrosis airway disease

Macrophages are the major resident immune cells in human airways coordinating responses to infection and injury. In cystic fibrosis, neutrophils are recruited to the airways shortly after birth, and actively exocytose damaging enzymes prior to chronic infection, suggesting a potential defect in macrophage immunomodulatory function.

Research

Defining the appropriate waiting time between multiple-breath nitrogen washout measurements

This letter addresses the recommendations by the American Thoracic Society & European Respiratory Society in 2005, that patients must wait 15-60mins between...

Research

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease.

Research

Stability Considerations for Bacteriophages in Liquid Formulations Designed for Nebulization

Pulmonary bacterial infections present a significant health risk to those with chronic respiratory diseases including cystic fibrosis and chronic-obstructive pulmonary disease. With the emergence of antimicrobial resistance, novel therapeutics are desperately needed to combat the emergence of resistant superbugs.

Research

Respiratory function in healthy Emirati children using forced oscillations

Forced oscillation technique measurements were feasible in Emirati school-children. New forced oscillation technique reference equation in Emirati children were derived.

Research

The all-age spirometry reference ranges reflect contemporary Australasian spirometry

Advances in statistical modelling have allowed the creation of smoothly changing spirometry reference ranges that apply across a wide age range and better...

Research

Influence of secular trends and sample size on reference equations for lung function tests

The aim of our study was to determine the contribution of secular trends and sample size to lung function reference equations, and establish the number...

Research

Clinical investigation of respiratory system admittance in preschool children

We compared the ability of Ars, to standard oscillatory outcomes, to determine respiratory disease and differentiate responses to inhaled bronchial challenges.

Research

Official ERS technical standards: Global Lung Function Initiative reference values for the carbon monoxide transfer factor for Caucasians

This is the largest collection of normative T LCO data, and the first global reference values available for T LCO.