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Research

Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis

A conditional analysis provided evidence for multiple associations within the HLA-DRB1-HLA-DQA1 region,and a model in which risk differed between three...

Research

Safety surveillance of influenza vaccine in pregnant women

Vaccination is the most effective strategy for preventing influenza infection in pregnancy.

Research

Parent–child book reading across early childhood and child vocabulary in the early school years

The current study investigated the extent to which low levels of joint attention in infancy and parent-child book reading across early childhood increase the...

Research

In utero exposure to arsenic alters lung development and genes related to immune and mucociliary function in mice

In utero exposure to arsenic via drinking water increases the risk of lower respiratory tract infections during infancy and mortality from bronchiectasis in...

Research

Alcohol-use disorders during and within one year of pregnancy: A population-based cohort study 1985-2006

Given the severe risks to the fetus from heavy prenatal alcohol exposure, assessment and recording of alcohol use should be routinely undertaken in maternity...

Research

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

Central corneal thickness (CCT) is associated with eye conditions including keratoconus and glaucoma.

Research

Genetic and functional evidence implicating DLL1 as the gene that influences susceptibility

Visceral leishmaniasis (VL) is caused by Leishmania donovani and Leishmania infantum chagasi. Genome-wide linkage studies from Sudan and Brazil identified...

Research

Sexual dimorphism in lung function responses to acute influenza A infection

Males are generally more susceptible to respiratory infections; however, there are few data on the physiological responses to such infections in males and...

Research

Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in children

Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.

Research

Gender-specific differences in adipose distribution and adipocytokines influence adolescent nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a predominantly adult-diagnosed disorder. Knowledge regarding the epidemiology, phenotype, and metabolic risk...