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Research

Der p 11 is a major allergen for house dust mite-allergic patients suffering from atopic dermatitis

House dust mites (HDMs) belong to the most potent indoor allergen sources worldwide and are associated with allergic manifestations in the respiratory tract.

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Will Global Climate Change Alter Fundamental Human Immune Reactivity: Implications for Child Health?

We postulate several mechanisms whereby climate change sensitive exposures and conditions will subtly impair aspects of the human immune response

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Perception of pediatric pain: A comparison of postoperative pain assessments between child, parent, nurse, and independent observer

Differences in the assessment of pediatric pain between children, parents, nurses, and independent observers in the acute postoperative setting

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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010

Reliable and timely information on the leading causes of death in populations, and how these are changing, is a crucial input into health policy debates.

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Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective Study

Antenatal testosterone exposure influences fetal neurodevelopment and gender-role behavior in postnatal life and may contribute to differences in...

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Group A Streptococcal Diseases and Their Global Burden

We review GAS transmission characteristics and prevention strategies, historical and geographical trends and report on the estimated global burden disease...

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A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010

Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a...

Research

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

Atopic dermatitis (AD) is a commonly occurring chronic skin disease with high heritability. Apart from filaggrin (FLG), the genes influencing atopic...

Research

Low intake of B-vitamins is associated with poor adolescent mental health and behaviour

The current prevalence of mental health problems in Western populations is approximately 20% and half of all adult mental health disorders are estimated to...

Research

A comparison of activity, participation and quality of life in children with and without spastic diplegia cerebral palsyNew Page

The aim of this study wa to measure activity, participation and QoL in children with CP and to determine how these differ from a comparable group of...