Search

Research

erology, predicting, Pseudomonas aeruginosa infection, young children, cystic fibrosis

News & Events

Seventeen-year-old Andrew says he has a better handle on managing his type 1 diabetes since taking part in an at-home research trial involving a sophisticated new pump system. Watch Andrew, his mum Leeanne and The Kids researcher Professor Tim Jones discuss the trial on Today Tonight.

News & Events

During National Diabetes Week, we take a look at diabetes distress and what research the Children's Diabetes Centre is doing to improve the mental health and wellbeing of young people with diabetes and their families.

Research

Rare diseases (RD) are conditions affecting fewer than 1 in 2000 persons, with over 7000 largely genetic RDs affecting 3.5 %-5.9 % of the global population, or approximately 262.9–446.2 million people. The substantial healthcare burden and costs, such as the $1 trillion annual expense in the USA, highlight the urgent need for improved RD management. The International Rare Diseases Research Consortium (IRDiRC) addresses this need through global collaboration, aiming for timely and accurate diagnosis, development of 1000 new therapies, and methodologies to measure impact by 2027.

Research

Citation: Sek K, Chen AXY, Cole T, Armitage JD, Tong J, ……… Waithman J, Parish IA, et al. Tumor site-directed A1R expression enhances CAR T cell

News & Events

ENDIA (Environmental Determinants of Islet Autoimmunity) is a national observational study into the causes of Type 1 Diabetes in childhood.

News & Events

New research led by The Kids' PhD student Matthew Cooper has found that some children with T1D have an increased risk of developing vascular diseases.

News & Events

Despite the unseasonal weather, good turnouts were recorded for recent events organised by PMH and Diabetes WA.

Research

Mitophagy preserves overall mitochondrial fitness by selectively targeting damaged mitochondria for degradation. The regulatory mechanisms that prevent PTEN-induced putative kinase 1 (PINK1) and E3 ubiquitin ligase Parkin (PINK1/Parkin)-dependent mitophagy and other selective autophagy pathways from overreacting while ensuring swift progression once initiated are largely elusive. 

Research

The pivotal phase 3 EPITOPE trial, a 12-month, double-blind, placebo-controlled study of epicutaneous immunotherapy with the VIASKIN patch containing 250 μg of peanut protein (VP250), previously reported significant treatment response versus placebo in peanut-allergic toddlers aged 1 through 3 years.