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Research
Realising the potential impact of artificial intelligence for rare diseases – A frameworkRare diseases (RD) are conditions affecting fewer than 1 in 2000 persons, with over 7000 largely genetic RDs affecting 3.5 %-5.9 % of the global population, or approximately 262.9–446.2 million people. The substantial healthcare burden and costs, such as the $1 trillion annual expense in the USA, highlight the urgent need for improved RD management. The International Rare Diseases Research Consortium (IRDiRC) addresses this need through global collaboration, aiming for timely and accurate diagnosis, development of 1000 new therapies, and methodologies to measure impact by 2027.
Research
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumorsCitation: Sek K, Chen AXY, Cole T, Armitage JD, Tong J, ……… Waithman J, Parish IA, et al. Tumor site-directed A1R expression enhances CAR T cell
News & Events
Get involved in ENDIAENDIA (Environmental Determinants of Islet Autoimmunity) is a national observational study into the causes of Type 1 Diabetes in childhood.
News & Events
Diabetes link to deadly diseasesNew research led by The Kids' PhD student Matthew Cooper has found that some children with T1D have an increased risk of developing vascular diseases.
News & Events
Ten Day Continuous Glucose Monitoring study – now recruitingThe Children’s Diabetes Centre is now recruiting for a new continuous glucose monitoring study.
News & Events
Congratulations Honours scholarship recipientsThe Rio Tinto Children’s Diabetes Centre; A JDRF Global Centre of Excellence (the Centre), announces inaugural Honours Scholarships for students dedicated to type 1 diabetes research.
News & Events
Better support for students with diabetesGreat news for children living with type 1 diabetes following the recent Federal Government announcement of a new $6m training and education program to make it easier for teachers to support students with diabetes in schools.
News & Events
DiAthlete Gavin Griffiths talks with ABC RadioLondon Olympics torchbearer Gavin Griffiths is living proof that a Type 1 Diabetes diagnosis is no obstacle to making the most out of life.
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Research
Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBADMitophagy preserves overall mitochondrial fitness by selectively targeting damaged mitochondria for degradation. The regulatory mechanisms that prevent PTEN-induced putative kinase 1 (PINK1) and E3 ubiquitin ligase Parkin (PINK1/Parkin)-dependent mitophagy and other selective autophagy pathways from overreacting while ensuring swift progression once initiated are largely elusive.