Search
Research
Worldwide variation in human milk metabolome: Indicators of breast physiology and maternal lifestyle?This study investigates the variation of human milk metabolites in human milk between five different countries
Research
The Canmore Declaration: Statement of Principles for Planetary HealthWe provide the Canmore Declaration, a Statement of Principles for Planetary Health
Research
Teleaudiology services for rehabilitation with hearing aids in adults: A systematic reviewThis review provides up-to-date evidence for teleaudiology hearing aid services in new and experienced hearing aid users in different practice settings
Research
Cellular and molecular mechanisms of vitamin D in food allergyEpidemiological evidence from the past decade suggests a role of vitamin D in food allergy pathogenesis
Research
β-Lactamase Tools for Establishing Cell Internalization and Cytosolic Delivery of Cell Penetrating PeptidesThe β-lactamase assays provide compatible tools for functional characterization of CPP activity and the delivery of biological cargos into cells
Research
Large-Scale Structural Variation Detection in Subterranean Clover Subtypes Using Optical MappingThe accuracy of structural variations detection by Bionano optical mapping is highly dependent on the quality of reference genomes and the density of selected nickases
Research
Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissionsThis is the first report examining the role of different rhinovirus species in ARIs in children admitted to a tertiary PICU
Research
Health and climate change MJA–Lancet Countdown report: Australia gets another failing grade in 2020 but shows signs of progressAt the end of 2019 and into 2020, catastrophic fires in Australia consumed homes, lives, wildlife, and land. Just as the fires subsided, Australia, like the rest of the world, faced another emergency—the COVID-19 pandemic. It is instructive to reflect on lessons from the health disasters of the past year. Following publication of the Lancet Countdown on Health and Climate Change, the Medical Journal of Australia (MJA)–Lancet Australian Countdown was published in December, 2020. This annual report on health and climate change in Australia is in its third year and comprises the efforts of five Australian institutions, in collaboration with University College London, UK, facilitated by a partnership between The Lancet and the MJA.
Research
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemiaCancer cells display DNA hypermethylation at specific CpG islands in comparison to their normal healthy counterparts, but the mechanism that drives this so-called CpG island methylator phenotype (CIMP) remains poorly understood. Here, we show that CpG island methylation in human T-cell acute lymphoblastic leukemia (T-ALL) mainly occurs at promoters of Polycomb Repressor Complex 2 (PRC2) target genes that are not expressed in normal or malignant T-cells and which display a reciprocal association with H3K27me3 binding.
Research
Feasibility and acceptability of the multi-component P3-MumBubVax antenatal intervention to promote maternal and childhood vaccination: A pilot studyThe P3-MumBubVax intervention is feasible and acceptable in the Australian public antenatal setting