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Prenatal alcohol exposure (PAE) is associated with growth deficits and neurodevelopmental impairment including foetal alcohol spectrum disorder (FASD). Difficulties with oral and written communication skills are common among children with PAE; however, less is known about how communication skills of adolescents who have PAE compare with those who do not.
The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transcription (STAT)3 signaling is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis, but the mechanisms regulating STAT3 expression and function are unknown. Suppressor of cytokine signaling (SOCS)1 and SOCS3 block STAT3, and low SOCS1 levels have been reported in IPF fibroblasts and shown to facilitate collagen production. Fibroblasts and lung tissue from IPF patients and controls were used to examine the mechanisms underlying SOCS1 down-regulation in IPF.
Investment in early childhood produces positive returns: for the child, the family and the community.
The current article outlines how individuals with fetal alcohol spectrum disorder may experience inequities within the justice system
Performance on neuropsychological measures may be useful for predicting persisting post-concussion symptoms
We found no increased risk of poor development among boys with hypospadias or undescended testis
Immune responses after the initial vaccination persisted for the 12 months studied, with little additional response after the booster dose at 6 months
This report provides new insight into the functional specialization within the broad network of dendritic cells that are responsible for skin immunosurveillance
Connective tissue growth factor (CTGF/CCN2) has been shown previously to be aberrantly expressed in a high proportion of paediatric precursor B cell acute...
This study investigated whether a prior bout of moderate-intensity exercise attenuates the glycemia-increasing effect of a maximal 30-sec sprint.