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Research
EphA3-targeted chimeric antigen receptor T cells are effective in glioma and generate curative memory T cell responsesHigh-grade gliomas including glioblastoma (GBM) and diffuse midline gliomas (DMG) represent the most lethal and aggressive brain cancers where current treatment modalities offer limited efficacy. Chimeric antigen receptor (CAR) T cell therapies have emerged as a promising strategy, boasting tumor-specific targeting and the unique ability to penetrate the blood-brain barrier.
News & Events
Launch of National Autism GuidelineResearchers from The Kids Research Institute Australia, working with the Autism CRC, have led the development of the National Guideline for the Assessment and Diagnosis of Autism Spectrum Disorder in Australia which was launched today.
Research
The role of social support in differentiating trajectories of adolescent depressed moodThis study explored the extent to which disaggregated support from family, peers, close friendships, teachers, and schools predicted membership into identified, sex-specific trajectories of depressed mood in 3210 Australian adolescents (49% females) based on self-report data collected at four annual time points from school Grade 6 to 9 (ages 10–16).
News & Events
Self-efficacy groups 2020Perth Children’s Hospital’s Diabetes Service has released the dates for its self-efficacy groups for 2020.
Research
Common Pathways to NSSI and Suicide Ideation: The Roles of Rumination and Self-CompassionThe salience of self-compassion offers promise for early intervention initiatives focusing on less judgmental or self-critical means of self-relation
Research
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the pregnancy and childhood epigenetics (PACE) consortiumwe meta-analysed the association between pre-pregnancy maternal BMI and methylation at over 450,000 sites in newborn blood DNA, across 19 cohorts.
Research
Climate clever clovers: New paradigm to reduce the environmental footprint of ruminants by breeding low methanogenic forages utilizing haplotype variationWe demonstrate the feasibility of a plant breeding approach without compromising animal productivity to mitigate enteric methane emissions, which is one of the most significant challenges to global livestock production.
Research
A pre-clinical model of resistance to induction therapy in pediatric acute lymphoblastic leukemiaRelapse and acquired drug resistance in T-cell acute lymphoblastic leukemia (T-ALL) remains a significant clinical problem.
Research
Methodological approach to exploring change in the Australia Early Development Instrument (AEDI): The estimation of a critical differenceThis report provides the technical details for the methodology calculated to determine "how big" a difference in the AEDI results between 2009 and 2012 is...
Research
Nutritional supplements during breastfeedingThe aim was to review the use of supplements during lactation and to document the use of nutritional supplements in a cohort of breastfeeding mothers.