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Research

Progression of early structural lung disease in young children with cystic fibrosis assessed using CT

Cross-sectional studies implicate neutrophilic inflammation and pulmonary infection as risk factors for early structural lung disease in infants and young...

Research

The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

The anti-inflammatory actions of IL-4 in activated human monocytes may reflect transcriptional regulation of genes involved in TLR signaling pathways.

Research

Nanoparticles and Children's Lungs: Is there a need for caution?

Nanoparticle research is currently an area of considerable interest due to the potential applications both in industry and medicine.

Research

The developing respiratory tract and its specific needs in regard to ultrafine particulate matter exposure

Nanoparticles have unique physico-chemical properties compared to larger particles that have the potential to provide promising new possibilities for...

Research

Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

The anti-inflammatory peptide, adrenomedullin (AM), and its cognate receptor are expressed in lung tissue, but its pathophysiological significance in airway...

Research

Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides

Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides.

Research

The association between neighborhood greenness and cardiovascular disease: An observational study

Previous studies have demonstrated links between cardiovascular disease and physical inactivity and poor air quality, which are both associated with...

Research

Research performance evaluation: The experience of an independent medical research institute

Evaluation of the social and economic outcomes of health research funding is an area of intense interest and debate...

Research

Young adults with intellectual disability transitioning from school to post-school: A literature review framed within the ICF

The purpose of this review was to describe literature relating to transition for young people with an intellectual disability and identify knowledge base gaps.

Research

Guidelines for pregnancy: What's an acceptable risk, and how is the evidence (finally) shaping up?

This paper reviews the evidence from systematic reviews and meta-analyses examining the risk from low and moderate levels of prenatal alcohol exposure.