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Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergyOur data indicate epigenetic dysregulation in the early stages of signal transduction through the T cell receptor complex, and likely reflects pathways modified by gene-environment interactions in food allergy
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Relevance of Aboriginal Peer-Led Parent Support: Strengthening the Child Environment in Remote AreasThis research highlights the critical emerging role of peer support workers in home visiting family support in a remote area of Australia
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Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissionsThis is the first report examining the role of different rhinovirus species in ARIs in children admitted to a tertiary PICU
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CASSETTE-clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: Study protocol for a randomised controlled trialThis study will assess the effect of adjunctive clindamycin on patient-centred outcomes in severe, toxin-mediated S. aureus infections
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Personalized transcriptomics reveals heterogeneous immunophenotypes in children with viral bronchiolitisDysregulated expression of IFN-dependent pathways after respiratory viral infections is a defining immunophenotypic feature of AVB-susceptible infants
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Impact of the 23-valent pneumococcal polysaccharide vaccination in pregnancy against infant acute lower respiratory infections in the Northern Territory of AustraliaWe assessed the impact of the 23-valent pneumococcal polysaccharide vaccine (23vPPV) in pregnancy against infant ALRI in this setting.
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Real-world outcomes of insulin pump compared to injection therapy in a population-based sample of children with type 1 diabetesPatients using insulin pump therapy had a better long-term glycemic control relative to the matched injection therapy cohort
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A marked shift in innate and adaptive immune response in chinese immigrants living in a western environmentThere is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years
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Use of Continuous Glucose Monitoring Trends to Facilitate Exercise in Children with Type 1 DiabetesThis study investigated the use of a carbohydrate intake algorithm based on continuous glucose monitoring trends during physical activity
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Insights into respiratory disease through bioinformaticsHere, we review the basic concepts in bioinformatics and genomic data analysis and illustrate the application of these tools to further our understanding of lung diseases