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Research

Early pulmonary inflammation and lung damage in children with cystic fibrosis

Airway inflammation and infection are present from early in life, often before children are symptomatic.

Research

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability

HRV-1B infection directly alters human airway epithelial TJ expression leading to increased epithelial permeability potentially via antiviral response of IL-15

Research

Probiotics for treatment and primary prevention of allergic diseases and asthma: looking back and moving forward

Review treatment and primary prevention studies, recent meta-analyses, and discuss the current understanding of the role of probiotics in this context

Research

Informing rubella vaccination strategies in East Java, Indonesia through transmission modelling

A single dose of rubella vaccine will take longer to reduce the burden of rubella and will be less robust to lower vaccine coverage

Research

Chronic HIV-1 infection induces B-cell dysfunction that is incompletely resolved by long-term antiretroviral therapy

B-cell dysfunction persists in patients with HIV receiving long-term antiretroviral therapy. the causes and consequences of this require further investigation.

Research

Effectiveness of seasonal trivalent influenza vaccination against hospital-attended acute respiratory infections in pregnant women

Influenza vaccination during pregnancy was associated with significantly fewer hospital attendances for ARI in pregnant women

Research

CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements

Identified CCI-007 as a novel small molecule that displays rapid toxicity towards a subset of MLL-r, CALM-AF10 and SET-NUP214 leukemia cell lines

Research

Levels of innate immune factors in preterm and term mothers' breast milk during the 1st month postpartum

Preterm breast milk contains significantly higher concentrations of some immune proteins than term breast milk

Research

Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms at long-term follow-up

This study found that differences in regional grey matter volume are discernible at an early stage of ultra-high risk psychosis

Research

Trends in smoking rates by level of psychological distress-time series analysis of US national health interview survey data 1997-2014

People with mental health problems have high rates of smoking, and represent a large proportion of adult smokers in the United States.