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Research
Genetic Manipulation of Group A Streptococcus-Gene Deletion by Allelic ReplacementAn optimized, rapid method for creating markerless isogenic mutations that combines Gibson assembly cloning with a new temperature-sensitive plasmid, pLZts
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Modelling factors for Aboriginal and Torres Strait Islander child neurodevelopment outcomes: A latent class analysisThis study highlights a range of unique profiles that can be used for improving the early development of young Aboriginal children
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Towards the development of an integrative, evidence-based suite of indicators for the prediction of outcome following mild traumatic brain injuryPerformance on neuropsychological measures may be useful for predicting persisting post-concussion symptoms
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Reading and numeracy attainment of children reported to child protection services: A population record linkage study controlling for other adversitiesA cross-agency response to supporting educational attainment for all children reported to child protection services is required
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The Deep Genome Project.The Deep Genome Project—to deliver the functional biological annotation of all human orthologous genomic elements in mice
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Early life determinants of health: Invest early to break the cycle of long-term disadvantage in neurodevelopmental disordersThis chapter discusses the importance of investment in early life determinants of health to break the cycle of long-term disadvantage. This chapter addresses these issues while focussing on neurodevelopmental disorders and their related mental health concerns as the targets at the centre of a biopsychosocial transformation of the health system.
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Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to DiagnosisIntervention for individuals with autism spectrum disorder (ASD) typically commences after diagnosis. No trial of an intervention administered to infants before diagnosis has shown an effect on diagnostic outcomes to date.
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Content Validation of Clinician-Reported Items for a Severity Measure for CDKL5 Deficiency DisorderCDKL5 deficiency disorder (CDD) results in early-onset seizures and severe developmental impairments. A CDD clinical severity assessment (CCSA) was previously developed with clinician and parent-report items to capture information on a range of domains.
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Barriers to influenza vaccination of children hospitalised for acute respiratory illness: A cross-sectional surveyTo identify barriers to influenza vaccination of children hospitalised for acute respiratory illness in Australia. A total of 595 parents of children hospitalised with acute respiratory illness across five tertiary hospitals in 2019 participated in an online survey. Multivariate logistic regression identified factors most strongly associated with influenza vaccination barriers.
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Use of linked administrative and laboratory data to confirm that serum 25(OH)D levels in pregnant women can be predicted from satellite estimates of ultraviolet radiationSerum 25 hydroxyvitamin D [25(OH)D] levels of pregnant women have been linked to various health outcomes in their offspring. Satellite-derived ultraviolet radiation (UVR) data have been used as a proxy for 25(OH)D levels, as individual-level cohort studies are time-consuming, costly and only feasible for common outcomes.