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Research

Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma model

We established a pipeline to assess the effects of epigenetic modifiers on CD8+ T cell proliferation, differentiation, and efficacy in a preclinical melanoma model

Research

Delivering Elder- and Community-Led Aboriginal Early Childhood Development Research: Lessons from the Ngulluk Koolunga Ngulluk Koort Project

We describe the application of a participatory action research methodology that is grounded in Aboriginal worldviews

Research

Pre-exposure prophylaxis for HIV prevention during pregnancy and lactation: forget not the women and children

The framework for appropriately identifying and managing at-risk pregnant and lactating women requiring PrEP is poorly defined

Research

Cochrane corner: platinum-induced hearing loss after treatment for childhood cancer

This systematic review shows that children treated with platinum analogues are at risk of developing hearing loss

Research

Indigenous compared with non-Indigenous Australian patients at entry to specialist palliative care: Cross-sectional findings from a multi-jurisdictional dataset

Indigenous patients are substantially underrepresented in care by services participating in the nationwide specialist palliative care Collaboration, likely reflecting widespread access barriers.

Research

Functional connectivity of the vigilant-attention network in children and adolescents with attention-deficit/hyperactivity disorder

ADHD patients showed substantially diminished intrinsic coupling for 7 connections and increased coupling for 4 connections

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Subjective memory complaints predict baseline but not future cognitive function over three years: Results from the Western Australia Memory Study

Subjective memory complaints individuals present distinctive features of memory complaints as compared to non-memory complainers

Research

The role of skin testing and extended antibiotic courses in assessment of children with penicillin allergy: An Australian experience

A direct oral provocation challenge with the culprit drug in Australian children can be safely performed, avoiding resource-intensive and painful skin testing

Research

BUILDING A STRONGER TOMORROW: Connecting our communities through Culture

Bring together experts, leaders and members of the national and international Indigenous community to identify culturally appropriate approaches to suicide prevention