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Research

Climate change, child health and the role of the paediatric profession in under-resourced settings

Climate change and its health impacts are increasingly recognised by the world's leading medical organisations and journals.

Research

Exploring the potential to use data linkage for investigating the relationship between birth defects and prenatal alcohol exposure

There was a significant association between maternal alcohol-related diagnoses recorded during pregnancy and ARBD, with an attributable fraction of 0.57%.

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A novel retro-inverso peptide is a preferential JNK substrate-competitive inhibitor

A novel 18 amino acid peptide PYC98 was demonstrated to inhibit JNK1 activity toward c-Jun.

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A time series analysis of presentations to Queensland health facilities for alcohol-related conditions, following the increase in 'alcopops' tax

We measured changes in admissions for alcohol-related harm to health throughout Queensland, before and after the tax increase in April 2008.

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The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

The anti-inflammatory actions of IL-4 in activated human monocytes may reflect transcriptional regulation of genes involved in TLR signaling pathways.

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Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

The anti-inflammatory peptide, adrenomedullin (AM), and its cognate receptor are expressed in lung tissue, but its pathophysiological significance in airway...

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Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides

Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides.

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Progression of early structural lung disease in young children with cystic fibrosis assessed using CT

Cross-sectional studies implicate neutrophilic inflammation and pulmonary infection as risk factors for early structural lung disease in infants and young...

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Vitamin D and atopy and asthma phenotypes in children

The purpose of this Review was to give an overview of the recent research into whether a lack of vitamin D contributes to the development of atopy and asthma...