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Research

An Expanded Conceptual Framework for Understanding Irritability in Childhood: The Role of Cognitive Control Processes

Children prone to irritability experience significant functional impairments and internalising and externalising problems. Contemporary models have sought to elucidate the underlying mechanisms in irritability, such as aberrant threat and reward biases to improve interventions. 

Research

Systematic Review and Meta-Analysis: Early Irritability as a Transdiagnostic Neurodevelopmental Vulnerability to Later Mental Health Problems

Irritability is a transdiagnostic indicator of child and adolescent internalizing and externalizing problems that is measurable from early life. The objective of this systematic review was to determine the strength of the association between irritability measured from 0 to 5 years and later internalizing and externalizing problems, to identify mediators and moderators of these relationships, and to explore whether the strength of the association varied according to irritability operationalization.

Research

The early Human Capability Index (eHCI)

The Early Human Capability Index is a holistic measure intended to capture early child development across diverse cultures and contexts.

Research

The ARC Centre of Excellence for Children and Families over the Life Course (Life Course Centre or LCC)

The Life Course Centre is a national centre funded by the Australian Research Council Centre of Excellence Scheme and hosted through the University of Queensland with collaborating nodes at the University of Western Australia, Sydney University and University of Melbourne.

News & Events

Telethon Institute joins international effort to improve early nutrition and long term health

The Kids for Child Health Research will join more than 50 scientists from 36 research institutions around the world to improve early nutrition

News & Events

Key appointments to drive early childhood collaboration

Leading child health researcher Professor Donna Cross has been appointed as Director of the new Early Childhood Development and Learning Collaboration, hosted b

News & Events

The Kids welcomes Minderoo investment in early child development

The Kids has congratulated Andrew & Nicola Forrest on their visionary commitment to develop a new blueprint for optimal child development in Aust & beyond.

News & Events

Early Years Initiative an unprecedented commitment to youngest West Australians

Minderoo Foundation and The Kids Research Institute Australia are proud to partner with the Western Australian Government on an unprecedented $49.3 million commitment to

Research

Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease

Genomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays.

Research

Skin-Microbiome Assembly in Preterm Infants during the First Three Weeks of Life and Impact of Topical Coconut Oil Application

The structure and function of infant skin is not fully developed until 34 weeks of gestation, and this immaturity is associated with risk of late-onset sepsis (LOS). Topical coconut oil improves preterm-infant skin integrity and may reduce LOS. However, data on early-life skin-microbiome succession and potential effects of emollient skin care in preterm infants are scarce.