Search
Research
Substantial intra‐individual variability in post‐prandial time to peak in controlled and free‐living conditions in children with Type 1 diabetesThe optimal time to bolus insulin for meals is challenging for children and adolescents with type 1 diabetes (T1D). Current guidelines to control glucose excursions do not account for individual differences in glycaemic responses to meals.
Research
Driving with Type 1 Diabetes: Real-World Evidence to Support Starting Glucose Level and Frequency of Monitoring During JourneysThere is limited evidence supporting the recommendation that drivers with insulin-treated diabetes need to start journeys with glucose >90 mg/dL. Glucose levels of drivers with type 1 diabetes were monitored for 3 weeks using masked continuous glucose monitoring (CGM).
Research
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweightWe find that DNA methylation in neonatal blood is associated with birthweight, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation
Research
Advances in Exercise and Nutrition as Therapy in DiabetesWe surveyed 2200 potentially eligible titles on PubMed and other common search engines for manuscripts on “exercise, nutrition, and diabetes” published between July 1, 2019, and June 30, 2020. This year's articles tended to focus on testing new applications for exercise management, including new insulin treatment approaches, wearables, and new smartphone applications.
Research
Comprehensive genetic screening: The prevalence of maturity-onset diabetes of the young gene variants in a population-based childhood diabetes cohortThis is the first comprehensive study of maturity-onset diabetes of the young variants in an unselected population-based pediatric diabetes cohort
Research
Characteristics of Automated Insulin Suspension and Glucose Responses with the Predictive Low-Glucose Management SystemLonger suspends and fewer glycemic excursions occur at night compared with day
Research
The COVID-19 Pandemic Affects Seasonality, With Increasing Cases of New-Onset Type 1 Diabetes in Children, From the Worldwide SWEET RegistryTo analyze whether the coronavirus disease 2019 (COVID-19) pandemic increased the number of cases or impacted seasonality of new-onset type 1 diabetes (T1D) in large pediatric diabetes centers globally.
Research
Associations between Prenatal Exposure to Phthalates and Features of the Metabolic Syndrome in Males from Childhood into AdulthoodPhthalate metabolites are detectable within the majority of the population. Evidence suggests that a prenatal exposure to phthalates may be associated with the subsequent risks of obesity and elevated blood pressure. We hypothesised that a prenatal exposure to phthalates would lead to an increase in adverse cardiometabolic parameters through childhood and adulthood.
Research
The Benefits to Bone Health in Children and Pre-School Children with Additional Exercise Interventions: A Systematic Review and Meta-AnalysisDetermine if exercise interventions, beyond what is already provided to children and preschool children, improve bone health and reduce fracture incidence.
Research
The glycaemic benefits of a very-low-carbohydrate ketogenic diet in adults with Type 1 diabetes mellitus may be opposed by increased hypoglycaemia risk and dyslipidaemiaThis study provides the first evidence that, ketogenic diets in adults with Type 1 diabetes are associated with excellent HbA1c levels and little glycaemic variability