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Research

Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumors

Acute lymphoblastic leukemia and childhood brain tumors are 2 of the most common forms of childhood cancer, but little is known of their etiology.

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The relationship between ambient ultraviolet radiation (UVR) and objectively measured personal UVR exposure dose is modified by season and latitude

Season and latitude modify the relationship between ambient ultraviolet radiation and personal ultraviolet radiation exposure

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T cells recognizing a 11mer influenza peptide complexed to H-2D b show promiscuity for peptide length

T-cell repertoire is selected according to self peptide-MHC (major histocompatibility complex) complexes in the thymus.

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ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure.

Two important risk factors for this disease are a positive family history and elevated intraocular pressure (IOP), which is also highly heritable.

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Cancer and mental illness: Key issues in mental health

Over many years, it has been shown that cancer represents a significant proportion of excess mortality for people with mental illness.

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Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin

Present a valuable resource for drug discovery and have identified ROM as a promising therapeutic for MLL-rearranged iALL

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Impact of adolescent peer aggression on later educational and employment outcomes in an Australian cohort

This study used prospective birth cohort data to analyse the relationship between peer aggression at 14 years of age and educational and employment outcomes...

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Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studies

Pregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to...

Research

Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomes

In this rhinovirus study, we first hypothesized that ex vivo human cells response to virus can serve as a proxy for otherwise controversial in vivo human...

Research

Prevalence and patterns of alcohol use in pregnancy in remote Western Australian communities: The Lililwan Project

Alcohol use in pregnancy is thought to be common in remote Australian communities, but no population-based data are available.