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Research

In Epigenomic Studies, Including Cell-Type Adjustments in Regression Models Can Introduce Multicollinearity, Resulting in Apparent Reversal of Direction of Association

Where cell types are highly correlated with other covariates in regression models, the statistical assumption of no multicollinearity may be violated

Research

Maternal Smoking During Pregnancy Induces Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic Risk

This study demonstrates a critical timing of cigarette smoke exposure over the life course for establishing persistent changes in DNA methylation into adolescence

Research

Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children

Bacterial airway microbiome is highly variable in early life and its role in wheeze remains less clear than viral influences

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Glutathione S-Transferase Genotype Protects against in Utero Tobacco-linked Lung Function Deficits

Certain glutathione S-transferase genotypes may have protective effects against the long-term deficits in lung function associated with in utero tobacco exposure

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Is autism one or multiple disorders?

Elucidating the underlying nature of the disorder(s) is a crucial step towards tailoring intervention to the biological and cognitive makeup of each individual.

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Locally derived traffic-related air pollution and fetal growth restriction: a retrospective cohort study

Fetal growth restriction has been inconsistently associated with maternal exposure to elevated levels of traffic-related air pollution.

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Evidence for the use of an algorithm in resolving inconsistent and missing Indigenous status in administrative data collections

We found that algorithms reduced the amount of missing data and improved within‑individual consistency.

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Missing voices: Profile and extent of acquired communication disorders in Aboriginal and non-Aboriginal adult stroke survivors in Western Australia

The needs of Aboriginal stroke patients with acquired communication disorder should inform appropriate service design for speech pathology and rehabilitation

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Declining transition rates to psychotic disorder in "ultra-high risk" clients: Investigation of a dilution effect

Later ultra-high risk psychosis cohorts presented with different clinical intake characteristics than earlier cohorts

Research

Analytical bias in the measurement of serum 25-hydroxyVitamin D concentrations impairs assessment of Vitamin D status

This publication demonstrated considerable differences in the measurement of 25-hydroxyvitamin D concentrations compared with a certified laboratory, even...