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A unique study purposely giving participants Streptococcus pyogenes (Strep A) to learn how much penicillin it takes to prevent infection has found the amount needed is much lower than previously thought – a discovery that will transform thinking on treatment for people living with rheumatic heart disease (RHD).
A new study underway at the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, is deliberately infecting tonsils with Strep A in the laboratory to test a range of potential vaccine candidates.
National research led by the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, has secured more than $3.4 million to assess the epidemiology of respiratory syncytial virus (RSV) throughout the country and optimise Australia’s immunisation strategy.
Wesfarmers Centre of Vaccines and Infectious Diseases researchers Dr Janessa Pickering and Dr August Mikucki travelled to Broome last week for the official launch of the long-awaited Missing Piece story books.
Perth investigators involved in a major global trial have launched an innovative Cultural Information Hub to maximise cultural safety for Aboriginal and/or Torres Strait Islander patients participating in research.
10,000 families participating in research by The Kids Research Institute Australia have demonstrated the effectiveness of a simple text message for increasing the number of children receiving their vaccinations on time.
Four The Kids Research Institute Australia researchers have received prestigious fellowships and four significant cohort studies led or co-led by The Kids have received key grants under two new funding programs supported by the State Government’s Future Health Research and Innovation (FHRI) Fund.
Antimicrobial resistance (AMR) is a global healthcare emergency, directly causing 1.3 million deaths per year and predicted to increase dramatically over the coming decades. Understanding the molecular mechanisms underpinning antibiotic resistance is central to approaches for AMR surveillance and diagnosis in a clinical laboratory.
Studies of traditional Indigenous compared to 'Western' gut microbiomes are underrepresented, and lacking in young children, limiting knowledge of early-life microbiomes in different cultural contexts. Here we analyze the gut metagenomes of 50 Indigenous Australian infants (median age <one year) living remotely with variable access to Western foods, compared to age- and sex-matched non-Indigenous infants living in urban Australia.
Cardiovascular diseases (CVDs) are the leading cause of mortality and are among the foremost causes of disability globally. CVD burden has continued to increase in most countries since 1990, with trends driven by changing exposures to harmful risk factors, population growth, and population aging.