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Research
Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adultsEpigenetic changes at the GFI1 were linked to smoking exposure in-utero/in-adulthood and robustly associated with cardio-metabolic risk factors
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Benefits of caseload midwifery to prevent fetal alcohol spectrum disorder: A discussion paperDrawing on previous research, caseload midwifery has potential to support the prevention of fetal alcohol spectrum disorder through continuity of care
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Applications of Immunopharmacogenomics: Predicting, Preventing, and Understanding Immune-Mediated Adverse Drug ReactionsIn this review, we present the latest evidence for human leukocyte antigen associations with Immune-mediated adverse drug reactions
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Effectiveness of a 3 + 0 pneumococcal conjugate vaccine schedule against invasive pneumococcal disease among a birth cohort of 1.4 million children in AustraliaOur population-based cohort study demonstrates that >90% coverage in the first year of a universal 3 + 0 PCV program provided high population-level protection
News & Events
Being active is key to heart healthDid you know that regular exercise can literally add years to the lives of children living with Type 1 Diabetes?
Research
A microbiome case-control study of recurrent acute otitis media identified potentially protective bacterial generaWe characterised the nasopharyngeal microbiome of these children in comparison to children with rAOM to identify potentially protective bacteria.
Research
The Cost of Control: Cost-effectiveness Analysis of Hybrid Closed-Loop Therapy in YouthHybrid closed-loop (HCL) therapy is an efficacious management strategy for young people with type 1 diabetes. However, high costs prevent equitable access. We thus sought to evaluate the cost-effectiveness of HCL therapy compared with current care among young people with type 1 diabetes in Australia.
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Bullying and mental health amongst Australian children and young people with cystic fibrosisThis study describes the peer bullying experiences of young people with CF, and examines associations between school bullying and the psychological well-being of these young people
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Telehealth for Audiological ManagementThis chapter focuses on the management of those with hearing impairment, and how tele-audiological tools and approaches may assist to improve service delivery
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Migration and work in postwar Australia: mortality profile comparisons between Australian and Italian workers exposed to blue asbestos at Wittenoom330,000 Italians arrived in Australia between 1945 and 1966, many on assisted passage schemes where the worker agreed to a 2 year unskilled employment contract.
Research
Aboriginal parent support: A partnership approachOur aim was to identify program elements, exploring participants’ perceptions of the program's suitability, feasibility, acceptability and effectiveness.
News & Events
Latitudinal gradient in childhood diabetesNew research from Perth's The Kids Research Institute Australia has shown the local relevance of a worldwide pattern of increased risk of childhood type 1 diabetes.
Research
Aboriginal children and penicillin injections for rheumatic fever: How much of a problem is injection pain?We explore young Aboriginal people's and clinicians' experience of injection pain for the 10 years of penicillin injections young people are prescribed.
News & Events
Have your say on exerciseAdolescents and young adults with Type 1 Diabetes are invited to be co-researchers at a summit to help develop the Children’s Diabetes Centre’s new exercise gui
Research
T-Cell Expression and Release of Kidney Injury Molecule-1 in Response to Glucose Variations Initiates Kidney Injury in Early DiabetesHalf of the mortality in diabetes is seen in individuals <50 years of age and commonly predicted by the early onset of diabetic kidney disease (DKD). In type 1 diabetes, increased urinary albumin-to-creatinine ratio (uACR) during adolescence defines this risk, but the pathological factors responsible remain unknown.
Research
Pleural Plaques and the Risk of Lung Cancer in Asbestos-exposed SubjectsThe presence of pleural plaques on radiologic imaging does not confer additional increase in the risk of lung cancer
Research
An evaluation of GPT models for phenotype concept recognitionClinical deep phenotyping and phenotype annotation play a critical role in both the diagnosis of patients with rare disorders as well as in building computationally-tractable knowledge in the rare disorders field.
News & Events
Community forum and symposium a big successThe Children’s Diabetes Centre was honoured to have leading international experts Laurel Messer and Professor Mike Riddell as guest speakers at its community forum and research symposium recently.
Research
The effect of TNF treatment uptake on incident hospital admission in Western AustraliaTreatment strategies for juvenile idiopathic arthritis (JIA) have shifted significantly over the last 20 years. We examined the effect of the introduction of government-subsidised TNF inhibitor (TNFi) treatment on incident hospitalisation for JIA.
