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Research

DeepEGFR a graph neural network for bioactivity classification of EGFR inhibitors

Epidermal Growth Factor Receptor (EGFR) plays a critical role in the development of several cancers. Thus, modulation/inhibition of EGFR activity is an appealing target of developing novel cancer therapeutics. 

Research

Life in a time of COVID: retrospective examination of the association between physical activity and mental well-being in western Australians during and after lockdown

The aim of this study was to examine physical activity and sedentary behaviours during Western Australia's COVID-19 lockdown and their association with mental well-being.

Research

Effect of single versus multistrain probiotic in extremely preterm infants: a randomised trial

Evidence indicates that multistrain probiotics benefit preterm infants more than single-strain (SS) probiotics. We assessed the effects of SS versus triple-strain (TS) probiotic supplementation (PS) in extremely preterm (EP) infants.

Research

The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheeze

A recently proposed method for classifying preschool wheeze is to describe it as either episodic (viral) wheeze or multiple trigger wheeze.

News & Events

Frangipani Family Day

Frangipani Family Day is an opportunity for CliniKids to celebrate the families we engage with through our clinical services and research.

News & Events

Being active is key to heart health

Did you know that regular exercise can literally add years to the lives of children living with Type 1 Diabetes?

Research

The Cost of Control: Cost-effectiveness Analysis of Hybrid Closed-Loop Therapy in Youth

Hybrid closed-loop (HCL) therapy is an efficacious management strategy for young people with type 1 diabetes. However, high costs prevent equitable access. We thus sought to evaluate the cost-effectiveness of HCL therapy compared with current care among young people with type 1 diabetes in Australia.

News & Events

Latitudinal gradient in childhood diabetes

New research from Perth's The Kids Research Institute Australia has shown the local relevance of a worldwide pattern of increased risk of childhood type 1 diabetes.

News & Events

Local researchers lead biggest ‘artificial pancreas’ outpatient study

The Children’s Diabetes Centre at The Kids Research Institute Australia is leading the longest and largest at-home trial of a hybrid closed-loop insulin pump system.

Research

The Benefits to Bone Health in Children and Pre-School Children with Additional Exercise Interventions: A Systematic Review and Meta-Analysis

Determine if exercise interventions, beyond what is already provided to children and preschool children, improve bone health and reduce fracture incidence.