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Predicting immune protection against outcomes of infectious disease from population-level effectiveness data with application to COVID-19

Quantifying the extent to which previous infections and vaccinations confer protection against future infection or disease outcomes is critical to managing the transmission and consequences of infectious diseases. We present a general statistical model for predicting the strength of protection conferred by different immunising exposures (numbers, types, and strains of both vaccines and infections), against multiple outcomes of interest, whilst accounting for immune waning. 

Predicting NSSI among trans young people: the role of transphobic experiences, body image, and gender dysphoria

Non-suicidal self-injury (NSSI) is particularly common among trans young people. NSSI is most commonly used as an emotion regulation strategy, which may explain the high prevalence of the behavior among trans young people, who often experience unique stressors. In the current study we test an application of the Pantheoretical Framework of Dehumanization, in which transphobic experiences, body surveillance, body dissatisfaction, and gender dysphoria are all theorized to predict NSSI.

How immunity shapes the long-term dynamics of influenza H3N2

Since its emergence in 1968, influenza A H3N2 has caused yearly epidemics in temperate regions. While infection confers immunity against antigenically similar strains, new antigenically distinct strains that evade existing immunity regularly emerge ('antigenic drift'). Immunity at the individual level is complex, depending on an individual's lifetime infection history.

ESM-Q: A consensus-based quality assessment tool for experience sampling method items

The experience sampling method (ESM) is increasingly used by researchers from various disciplines to answer novel questions about individuals’ daily lives. Measurement best practices have long been overlooked in ESM research, and recent reviews show that item quality is often not reported in ESM studies. The absence of information about item quality may be partly explained by the lack of consensus on how ESM item quality should be evaluated.

The decades old program helping families and kids to thrive

It’s a brave move to upend your entire family to seek a fresh start – or safety – in a new country: even braver when the country you’re moving to has a completely different language, structure and cultural outlook.

Applying the arts to wild little hearts

When author Maurice Sendak first sketched out the story of a rambunctious little boy sent to his room without supper, there’s no way he could have known his rollercoaster tale of childhood imagination would still be speaking to the hearts of wild young things more than six decades on.

Community and action at the heart of Journey Together project

A unique initiative is combining research, action and advocacy to deliver evidence- based improvements to the health and wellbeing of Aboriginal families in Perth and Western Australia’s north west.

Unravelling medical mysteries for kids with undiagnosed diseases

Three hundred and fifty million people live with an undiagnosed disease worldwide and three quarters of them are children.

Putting malaria on the MAP

The Kids Research Institute Australia is at the forefront of a global effort to track and prevent malaria – one of the world’s leading causes of disease and child deaths, particularly in developing countries.

Could a vaccine help fight food allergies?

A dramatic rise in food allergies over the past 20 years had Australian medical professionals scratching their heads, with three in every ten babies born each year developing food-related allergy or eczema.