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Research

Ontogeny of toll-like and NOD-like receptor-mediated innate immune responses in Papua New Guinean infants

Studies addressing the ontogeny of the innate immune system in early life have reported mainly on Toll-like receptor (TLR) responses in infants living in...

Research

No association between early gastrointestinal problems and autistic-like traits in the general population

No association between early gastrointestinal problems and autistic-like traits in the general population, determine whether gastrointestinal problems, early...

Research

Validity and Psychometric Properties of the Early Development Instrument in Canada, Australia, United States, and Jamaica

There is an increasing support from international organizations and the research community for stepping beyond infant or child mortality as the most common...

Research

Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease

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Expanding the clinical picture of the MECP2 Duplication syndrome

Perinatal characteristics, early childhood development and medical co-morbidities in MECP2 Duplication syndrome

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The associations between physical activity, screen time and weight from 6 to 14 yrs: The Raine Study

To examine the strength and direction of the relationship between physical activity level, screen use and BMI in a cohort at ages 6, 8, 10 and 14 yrs as part...

Research

25-hydroxyvitamin D status of pregnant women is associated with the use of antenatal vitamin supplements and ambient ultraviolet radiation

Vitamin D deficiency in a predominantly white Caucasian cohort of pregnant women is less prevalent than has been reported in other studies

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Systematic review and meta-analysis of respiratory viral coinfections in children

Coinfection is not associated with increased clinical severity, but further investigations by pathogen pairs are warranted

Research

Early life rhinovirus infection exacerbates house-dust-mite induced lung disease more severely in female mice

Early life rhinovirus infection influences the development of house-dust-mite induced lung disease in female, but not male mice

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Clinical guidelines for management of bone health in rett syndrome based on expert consensus and available evidence

A clinically significant history of fracture in combination with low bone densitometry findings is necessary for a diagnosis of osteoporosis in Rett Syndrome