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Prolonged school non-attendance in adolescence: a practical approachProlonged school non-attendance in adolescence is complex and represents a critical public health problem due to the range of associated adverse poor outcomes
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Early life rhinovirus infection exacerbates house-dust-mite induced lung disease more severely in female miceEarly life rhinovirus infection influences the development of house-dust-mite induced lung disease in female, but not male mice
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The PneuCarriage Project: A Multi-Centre Comparative Study to Identify the Best Serotyping Methods for Examining Pneumococcal CarriageThe PneuCarriage project, a large, international multi-centre study for the identification of the best pneumococcal serotyping methods for carriage studies
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Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter UsageThis study helps us understand how cancer cells are regulated by key genes and their corresponding networks to alter their fate in response to specific...
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Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastaseFree NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease
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A novel BRD4-NUT fusion in an undifferentiated sinonasal tumor highlights alternative splicing as a contributing oncogenic factor in NUT midline carcinomaIn this study, we report the case of an adolescent NMC patient presenting with severe facial pain, proptosis and visual impairment due to a mass arising from...
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GFP-complementation assay to detect functional CPP and protein delivery into living cells.Efficient cargo uptake is essential for cell-penetrating peptide (CPP) therapeutics, which deliver widely diverse cargoes by exploiting natural cell...
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Adverse metabolic phenotype of adolescent girls with non-alcoholic fatty liver disease plus polycystic ovary syndrome compared with other girls and boysNon-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) share risk associations of adiposity and insulin resistance.
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Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cellsMature B cells, CR2/CD21 transcription proceeds from a focused TSS regulated by a non-consensus TATA box, an initiator element and downstream promoter element
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Strabismus, a preventable barrier to social participation: A short reportIsolated strabismus does not significantly impair visual functionality and has traditionally been considered a primarily cosmetic defect of little importance.