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Research

Vitamin D C3-epimer levels are proportionally higher with oral vitamin D supplementation compared to ultraviolet irradiation of skin in mice but not humans

The proportion of 25(OH)D3 that undergoes epimerization is greater with oral vitamin D3 supplementation than exposure to UVR in mice, but not in humans

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Applications of Immunopharmacogenomics: Predicting, Preventing, and Understanding Immune-Mediated Adverse Drug Reactions

In this review, we present the latest evidence for human leukocyte antigen associations with Immune-mediated adverse drug reactions

Research

Misgendering and experiences of stigma within health care settings for transgender individuals

Misgendering within the health care system can significantly affect the mental and physical health of transgender individuals

Research

Differences in stroke risk and cardiovascular mortality for Aboriginal and other Australian patients with atrial fibrillation

Stroke risk and cardiovascular mortality are markedly higher for Aboriginal than non-Aboriginal patients with atrial fibrillation, particularly for patients under 60

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Rheumatic heart disease in pregnancy: Profile of women admitted to a Western Australian tertiary obstetric hospital

This retrospective study assessed maternal and perinatal outcomes for women with rheumatic heart disease admitted to the largest tertiary obstetric hospital

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Sun-immune connection

Exposure to ultraviolet radiation damages skin cell DNA but skin cancers develop because ultraviolet radiation also affects the immune system

Research

Vitamin D receptor polymorphisms are associated with severity of wheezing illnesses and asthma exacerbations in children

These findings suggest that genetic variants at the VDR locus may play a role in acute wheeze/asthma severity in children

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The detection of bile acids in the lungs of paediatric cystic fibrosis patients is associated with altered inflammatory patterns

Our work has identified a clinically relevant host-derived factor that may participate in shaping early events in the aetiology of CF respiratory disease

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Impact of multidrug-resistant tuberculosis and its medications on adverse maternal and perinatal outcomes: Protocol for a systematic review and meta-Analysis

We aim to determine whether multidrug-resistant tuberculosis and its medications during pregnancy impact maternal and perinatal outcomes

Research

A spatio-temporal analysis to identify the drivers of malaria transmission in Bhutan

Hot spots and clusters of both species were isolated in the central southern part of Bhutan bordering India