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Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 yearsHuman perinatal life is characterized by a period of extraordinary change during which newborns encounter abundant environmental stimuli and exposure to potential pathogens. To meet such challenges, the neonatal immune system is equipped with unique functional characteristics that adapt to changing conditions as development progresses across the early years of life, but the molecular characteristics of such adaptations remain poorly understood.
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Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profilesthe association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories
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Invasive fungal infections in children with acute lymphoblastic leukaemia: Results from four Australian centres, 2003-2013Invasive fungal infections are more common in children with high-risk acute lymphoblastic leukaemia and in relapsed disease
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Parental experiences using the Therapy Outcomes by You (TOBY) application to deliver early intervention to their child with autismParental experience of TOBY was positive when use of the application aligned with parental proficiency, opportunities for use, and importantly, the needs of the child
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The Australian and New Zealand Children's Haematology/Oncology Group Biobanking NetworkThe ANZCHOG-BN was developed to improve and streamline access to high quality pediatric and adolescent/young adult cancer biospecimens for cancer research
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Production of IgG2 Antibodies to Pneumococcal Polysaccharides After Vaccination of Treated HIV Patients May Be Augmented by IL-7Rα Signaling in ICOS + Circulating T-CellsOur findings suggest that utilization of IL-7 by cTFH cells affects production of IgG2 antibodies to PPV23 antigens in some HIV patients
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The epidemiological transition in Papua New Guinea: new evidence from verbal autopsy studiesOur results indicate immediate priorities for health service planning and for strengthening of vital registration systems
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Folate Status and Neural Tube Defects in Aboriginal Australians: The Success of Mandatory Fortification in Reducing a Health DisparityMandatory flour fortification with folic acid in 2009, led to further reductions in overall neural tube defects
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Intact spontaneous emotional expressivity to non-facial but not facial stimuli in schizophrenia: An electromyographic studyThe results indicate that schizophrenia is marked by a disruption in rapid facial responding to facial expressions, but intact responding to non-facial emotional stimuli
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Associations between major dietary patterns and testicular function in a population-based cohort of young men: results from the Western Australian Pregnancy Cohort StudyA potential negative association of a “Western” dietary pattern with male reproductive health was detected