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Research

International consensus (ICON) on: Clinical consequences of mite hypersensitivity, a global problem

The objectives of this document are to highlight aspects of mite biology that are clinically relevant and to update the current knowledge on mite allergens

Research

What is the evidence for managing tone in young children with, or at risk of developing, cerebral palsy: a systematic review

To conduct a systematic review of the evidence for the management of tone in infants 0-24 months of age, with or at risk of developing cerebral palsy.

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Neuroanatomical Predictors of Functional Outcome in Individuals at Ultra-High Risk for Psychosis

The poorest functional outcomes have the lowest grey matter densities at identification as ultra-high risk for psychosis

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Sialic acid-to-urea ratio as a measure of airway surface hydration

We explored a robust method to estimate mucus hydration using sialic acid as a marker for mucin content.

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Congenital Cytomegalovirus among Children with Cerebral Palsy

To determine the proportion of children with CP and CMV, taking various factors into account.

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Lost in translation: translational interference from a recurrent mutation in exon 1 of MECP2

Rett syndrome (RTT) is an X linked neuro-developmental disorder affecting mostly girls. Mutations in the coding region of MECP2 are found in 80% of classic...

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The broader language phenotype of Autism: A comparison with Specific Language Impairment

Some individuals with autism spectrum disorders (ASD) experience linguistic difficulties similar to those found in individuals with specific language...

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Hypoxia and sterile inflammation in cystic fibrosis airways: Mechanisms and potential therapies

In this review, we consider recent evidence regarding hypoxia and sterile inflammation in cystic fibrosis airways

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Safety and immunogenicity of a combined DTPa-IPV vaccine administered as a booster from 4 years of age: a review

A combined DTPa-IPV booster vaccine was administered as a 4th or 5th dose after DTPa or DTPw priming.