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Research
A phase 3, multicenter, randomized, double-blind study to evaluate the interchangeability of V114, a 15-valent pneumococcal conjugate vaccine, and PCV13 with respect to safety, tolerability, and immunogenicity in healthy infants (PNEU-DIRECTION)Pneumococcal disease (PD) remains a major health concern globally. In children, pneumococcal conjugate vaccines (PCVs) provide protection against PD from most vaccine serotypes, but non-vaccine serotypes contribute to residual disease. V114 is a 15-valent PCV containing all 13 serotypes in Prevnar 13™ and public health important serotypes 22F and 33F. This phase 3 study evaluated safety and immunogenicity of mixed PCV13/V114 regimens using a 3 + 1 dosing schedule when changing from PCV13 to V114 at doses 2, 3, or 4.
Research
Ambient Air Pollution, Extreme Temperatures and Birth Outcomes: A Protocol for an Umbrella Review, Systematic Review and Meta-AnalysisPrenatal exposure to ambient air pollution and extreme temperatures are among the major risk factors of adverse birth outcomes and with potential long-term effects during the life course. Although low- and middle-income countries (LMICs) are most vulnerable, there is limited synthesis of evidence in such settings. This document describes a protocol for both an umbrella review (Systematic Review 1) and a focused systematic review and meta-analysis of studies from LMICs (Systematic Review 2).
News & Events
The PERSIST StudyThe Persist Study Community Workshop. Help us to understand how to engage other youth who live with T1D!
News & Events
New Study: Water Survey UWAThere is evidence that physical activity is well known to increase the risk of hypoglycaemia in people with type 1 diabetes. However, little is known about the effect of water-based activities on blood glucose levels.
News & Events
New study: Diabetes stress and coping strategiesThe Children’s Diabetes Centre is investigating the ways young people, and their primary carers, cope with stressors associated with type 1 diabetes.
Research
Lung function in African infants in the Drakenstein child health study impact of lower respiratory tract illnessEarly life lower respiratory tract illness impairs lung function at 1 year, independent of baseline lung function
News & Events
New Eye ClinicThere's a new children’s clinic to revolutionise diabetic eye treatment here in WA. The clinic is a collaboration between the Lions Eye Institute
News & Events
Welcome Craig!There’s a new face in Perth Children’s Hospital’s diabetes clinic – meet consultant paediatric endocrinologist Dr Craig Taplin! We asked Craig a few questions to help to get to know him better and find out what drew him to Perth.
News & Events
Insulin pump helps to predict and prevent hyposNew research from the Children’s Diabetes Centre has found a pump that suspends insulin delivery when BGLs fall can halve the incidence of hypoglycaemia.
Research
'If I Wanted to Have More Opportunities and Go to a Better School, I Just Had to Get Used to It’The experiences of 32 male Aboriginal students from regional and remote towns and communities while they attended a metropolitan boarding school...