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Research

A phase 3, multicenter, randomized, double-blind study to evaluate the interchangeability of V114, a 15-valent pneumococcal conjugate vaccine, and PCV13 with respect to safety, tolerability, and immunogenicity in healthy infants (PNEU-DIRECTION)

Pneumococcal disease (PD) remains a major health concern globally. In children, pneumococcal conjugate vaccines (PCVs) provide protection against PD from most vaccine serotypes, but non-vaccine serotypes contribute to residual disease. V114 is a 15-valent PCV containing all 13 serotypes in Prevnar 13™ and public health important serotypes 22F and 33F. This phase 3 study evaluated safety and immunogenicity of mixed PCV13/V114 regimens using a 3 + 1 dosing schedule when changing from PCV13 to V114 at doses 2, 3, or 4. 

Research

Ambient Air Pollution, Extreme Temperatures and Birth Outcomes: A Protocol for an Umbrella Review, Systematic Review and Meta-Analysis

Prenatal exposure to ambient air pollution and extreme temperatures are among the major risk factors of adverse birth outcomes and with potential long-term effects during the life course. Although low- and middle-income countries (LMICs) are most vulnerable, there is limited synthesis of evidence in such settings. This document describes a protocol for both an umbrella review (Systematic Review 1) and a focused systematic review and meta-analysis of studies from LMICs (Systematic Review 2).

News & Events

The PERSIST Study

The Persist Study Community Workshop. Help us to understand how to engage other youth who live with T1D!

News & Events

New Study: Water Survey UWA

There is evidence that physical activity is well known to increase the risk of hypoglycaemia in people with type 1 diabetes. However, little is known about the effect of water-based activities on blood glucose levels.

News & Events

New study: Diabetes stress and coping strategies

The Children’s Diabetes Centre is investigating the ways young people, and their primary carers, cope with stressors associated with type 1 diabetes.

Research

Is sport an untapped resource for recovery from first episode psychosis? A narrative review and call to action

Sport-based interventions could be an opportunity to provide intervention to individuals recovering from their first psychotic episode

News & Events

Combating glucose rises after meals - new study

Participants are needed for a new Children's Diabates Centre study looking at the patterns in glucose rise after meals.

News & Events

Family’s fundraising efforts a hole-in-one

When Meghan Bunter’s daughter was first diagnosed with diabetes, she felt overwhelmed not only with Ella’s diagnosis but also the flood of donation requests.

Research

Age at diagnosis of birth defects

Many birth defects surveillance programs ascertain cases of birth defects diagnosed beyond 1 year of age.

School experience studies

Besides the challenges associated with their teenage years, adolescents with Type 1 Diabetes (T1D) encounter additional challenges of having a chronic condition.