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The role of coping in the association between subclinical psychotic experiences and functioning: A within study replication in two independent adolescent samplesThe within study replication consistently found that coping style mediates subclinical psychotic experiences and psychosocial functioning
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Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adultsEpigenetic changes at the GFI1 were linked to smoking exposure in-utero/in-adulthood and robustly associated with cardio-metabolic risk factors
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Investigation of group A Streptococcus immune responses in an endemic setting, with a particular focus on J8We analysed the stimulation of J8 antibodies in response to infection, and the role of existing J8 antibodies in protection against subsequent infection
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Elizabeth Usher Memorial Lecture: Rethinking the clinical pathway for autism spectrum disorder and challenging the status quoThe aim of the paper is to outline the future of early identification and intervention of ASD and the research goals to be addressed to achieve this vision.
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Using record linkage to examine testing patterns for respiratory viruses among children born in Western AustraliaUsing linked data, we describe changes in respiratory virus testing among children born in Western Australia in 1996-2012
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Maternal Alcohol Use Disorder and Risk of Child Contact with the Justice System in Western Australia: A Population Cohort Record Linkage StudyChildren who were exposed to a maternal alcohol use disorder had significantly increased odds of contact with the justice system.
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Expression profiling of Sudanese visceral leishmaniasis patients pre- and post-treatment with sodium stibogluconateThese results contribute to our understanding of immunopathology associated with visceral leishmaniasis and response to sodium stibogluconate treatment
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The intersect of genetics, environment, and microbiota in asthma-perspectives and challengesIn asthma, a significant portion of the interaction between genetics and environment occurs through microbiota. The proposed mechanisms behind this interaction are complex and at times contradictory. This review covers recent developments in our understanding of this interaction: the "microbial hypothesis" and the "farm effect"; the role of endotoxin and genetic variation in pattern recognition systems; the interaction with allergen exposure; the additional involvement of host gut and airway microbiota; the role of viral respiratory infections in interaction with the 17q21 and CDHR3 genetic loci; and the importance of in utero and early-life timing of exposures.
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Can the CHA2 DS2 -VA schema be used to decide on anticoagulant therapy in Aboriginal and other Australians with non-valvular atrial fibrillation?The Australasian guidelines recommend use of the CHA2 DS2 -VA schema to stratify ischaemic stroke risk in patients with non-valvular atrial fibrillation (N-VAF) and determine risk thresholds for recommending oral anticoagulant (OAC) therapy. However, the CHA2 DS2 -VA score has not been validated in a representative Australian population cohort with N-VAF, including in Aboriginal people who are known to have a higher age-adjusted stroke risk than other Australians.
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Enteral Vitamin A for Reducing Severity of Bronchopulmonary Dysplasia: A Randomized TrialEvidence suggests that intramuscular vitamin A reduces the risk of bronchopulmonary dysplasia (BPD) in preterm infants. Our objective was to compare enteral water-soluble vitamin A with placebo supplementation to reduce the severity of BPD in extremely preterm infants.