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Toll-like receptor 7 function is reduced in adolescents with asthmaAnti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood.
Research
Nothing but fear itself: parental fear as a determinant of child physical activity and independent mobilityOver the past decade we have seen declining rates in child engagement in physical activity with escalating health problems ensuing.
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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes riskLevels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide...
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Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growthAnti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory.
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The importance of environment on respiratory genotype/phenotype relationships in the InuitThis study aimed to investigate the effects of different macro-environments on asthma genotype-phenotype associations in 2 geographically separated populations
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Prevalence of and risk factors for human rhinovirus infection in healthy aboriginal and non-aboriginal western australian childrenHuman rhinovirus (HRV) species C (HRV-C) have been associated with frequent and severe acute lower respiratory infections and asthma in hospitalized children.
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A retrospective population-based cohort study identifying target areas for prevention of acute lower respiratory infections in childrenAcute lower respiratory infections (ALRI) are a major cause of hospitalisation in young children
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Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multipleDissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21We performed...
Research
Prenatal maternal stress associated with ADHD and autistic traits in early childhoodResearch suggests that offspring of mothers who experience high levels of stress during pregnancy are more likely to have problems in neurobehavioral...