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‘Boom Boom’ goes the beat towards ending rheumatic heart disease

A song written by kids in Barunga as part of the END RHD Communities Project is helping prevent the spread of infections that cause rheumatic heart disease in remote Aboriginal Communities.

It takes a village: how the CRE helped shape FASD policy and practice

The FASD Research Australia Centre of Research Excellence (CRE) has substantially built the evidence base around FASD and had a significant impact on advocacy, policy and practice.

New policy helps kids huff and puff their way to stronger, healthier bodies and brains

Childcare centres have flocked to take up a new evidence-based policy to help ensure young children get more of the physical activity they need to be healthy and developmentally on track.

Unlocking the benefit of genomics for Indigenous Australians

Scientific discoveries over the past 30 years mean doctors now have a deeper understanding of what causes disease and how those diseases might progress.

Standing up to a cruel DISEASE

Klair Bayley knew her son Logan would eventually need a wheelchair.

Research offers new hope for babies with rare leukaemia

A pilot clinical study has found an immunotherapy drug can dramatically increase survival rates for babies with a rare form of leukaemia, paving the way for a major international clinical trial.

Research

Subcutaneous Infusion of Benzathine Penicillin G Is Acceptable and Preferred Over Intramuscular Injections for Syphilis in Western Australian Sexual Health Clinic Attendees

Controlling the syphilis epidemic in Australia is a public health priority. Regular intramuscular (IM) injections of benzathine penicillin G (BPG) are the current standard of care for late latent syphilis in Australia; however, repeated IM BPG injections are painful, and treatment completion rates are low. Early-phase clinical trials have demonstrated the tolerability and safety of high-dose subcutaneous infusions of BPG (SCIP), where the total treatment dose can be delivered at a single visit. Here we describe the experiences and preferences of attendees of Western Australian sexual health clinics in the Perth metropolitan region who have syphilis and were treated with SCIP.

Research

Establishing the lowest penicillin concentration to prevent pharyngitis due to Streptococcus pyogenes using a human challenge model (CHIPS)

The in-vivo plasma concentration of penicillin needed to prevent Streptococcus pyogenes pharyngitis, recurrent acute rheumatic fever, and progressive rheumatic heart disease is not known. We used a human challenge model to assess the minimum penicillin concentration required to prevent streptococcal pharyngitis.

Research

Development, construct validity and utility of a cross-culturally adapted Otitis Media-6 (OM-6) questionnaire for urban Aboriginal and/or Torres Strait Islander children

Tamara Chris Valerie Veselinovic Brennan-Jones Swift BSc(Hons) MClinAud PhD PhD Clinical Research Fellow Head, Ear and Hearing Health Aboriginal

Research

Ecological-level factors associated with tuberculosis incidence and mortality: A systematic review and meta-analysis

Globally, tuberculosis (TB) is the leading infectious cause of morbidity and mortality, with the risk of infection affected by both individual and ecological-level factors. While systematic reviews on individual-level factors exist, there are currently limited studies examining ecological-level factors associated with TB incidence and mortality. This study was conducted to identify ecological factors associated with TB incidence and mortality.