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Universal paediatric refugee health screeningIn this note we briefly outline our recent experience with paediatric refugee screening in Western Australia (WA) based on the frameworks outlined previously.
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Prevalence of and risk factors for human rhinovirus infection in healthy aboriginal and non-aboriginal western australian childrenHuman rhinovirus (HRV) species C (HRV-C) have been associated with frequent and severe acute lower respiratory infections and asthma in hospitalized children.
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Reduction in disparity for pneumonia hospitalisations between Australian indigenous and non-Indigenous childrenIn the 1990s pneumonia hospitalisation rates in Western Australia (WA) were 13 times higher in Indigenous children than in non-Indigenous children...
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Ontogeny of toll-like and NOD-like receptor-mediated innate immune responses in Papua New Guinean infantsStudies addressing the ontogeny of the innate immune system in early life have reported mainly on Toll-like receptor (TLR) responses in infants living in...
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Hospitalisation for bronchiolitis in infants is more common after elective caesarean deliveryThe authors previously reported an increased risk of hospitalisation for acute lower respiratory infection up to age 2 years in children delivered by...
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Proteomics confirms immune stabilizing effects of narrowband UVB treatment in patients with clinically isolated syndrome and multiple sclerosisMultiple sclerosis (MS) demonstrates a latitude gradient in prevalence and severity, implicating ultraviolet B (UVB) exposure and photoimmune mechanisms in disease risk and progression. While narrowband (NB)-UVB phototherapy has long stabilized inflammation in dermatology, its systemic immunomodulatory effects in MS remain incompletely defined.
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Achieving cultural safety in genetic counseling for Aboriginal and Torres Strait Islander people in AustraliaGlobally, Indigenous people, including Aboriginal and Torres Strait Islander people in Australia, experience significantly poorer health outcomes than their non-Indigenous counterparts. In part, this can be attributed to the ongoing impacts of colonization, marginalization, and systemic discrimination. In the genomic healthcare era, Indigenous people remain underrepresented in public genetic health services, raising concerns about cultural competency and inclusivity within the genetic counseling profession.
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Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanomaA range of microbiota species correlate with improved cancer outcomes in patients and confer protection in pre-clinical mouse models. Here, we examined how microbiota regulate CD8+ T cell immunity against melanoma. Spontaneous control of cutaneous melanoma in mice correlated with metabolic pathways required for microbial synthesis of short-chain fatty acids (SCFAs) shared between several microbiota species.
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Development of the Breastfed Infant Oral Microbiome Is Associated with Concentrations and Intakes of Human Milk OligosaccharidesHuman milk oligosaccharides (HMOs) are bioactive carbohydrates abundant in human milk that shape the infant gut microbiome, yet their influence on the oral microbiome remains poorly understood. This study investigated associations between HMO concentrations and infant HMO intakes and the composition of the oral microbiome in predominantly and exclusively breastfed infants.
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Change in Diet Quality and Dietary Intake From Pregnancy to 1-Year Postpartum: A Longitudinal Analysis in Australian WomenThis longitudinal analysis in Australian women evaluated change in diet quality and food and nutrient intakes from the third trimester of pregnancy to 1-year postpartum with comparison to national nutrition recommendations. Associations between diet quality, sociodemographic and health characteristics were also investigated.