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Research

A framework for understanding quality of life domains in individuals with the CDKL5 deficiency disorder

This study aimed to identify the quality of life domains important for individuals with CDKL5 deficiency disorder

Research

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained

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Poverty, Parental Mental Health and Child/Adolescent Mental Disorders: Findings from a National Australian Survey

The purpose of this study is to examine the association between poverty and child mental disorders

Research

Clinical Ecology-Transforming 21st-Century Medicine with Planetary Health in Mind

The grand, interconnected challenges of our time demands that all of medicine be viewed from an ecological perspective

Research

Apgar score and risk of autism

This study suggests that low Apgar score is associated with higher risk of autism spectrum disorder, and in particular autistic disorder

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Baseline incidence of adverse birth outcomes and infant influenza and pertussis hospitalisations prior to the introduction of influenza and pertussis vaccination

These baseline data are essential to assess the safety and effectiveness of influenza and pertussis vaccinations in pregnant women from the NT

Research

Group A Streptococcus co-ordinates manganese import and iron efflux in response to hydrogen peroxide stress

Here, we demonstrate that group A Streptococcus (GAS) utilises Mn(II) import via MtsABC during conditions of hydrogen peroxide stress

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Features of the metabolic syndrome in late adolescence are associated with impaired testicular function at 20 years of age

Adolescents with features of metabolic disorder or insulin resistance show impaired testicular function and altered hormone levels

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The politics of picking: Selective vaccinators and population-level policy

Public health systems face tensions between individuals and the collective. Parents who selectively vaccinate demonstrate this tension

Research

CDKL5 variants: Improving our understanding of a rare neurologic disorder

Providing new insights into the interpretation of genetic variants in a rare neurologi disorder, in the contexts of population sequencing data.