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Showing results for "8"

Research

Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement

Standards and consensus recommendations are presented for manufacturers, clinicians, operators, and researchers

Research

Impact of Childhood Pneumococcal Conjugate Vaccine on Nonnotified Clinically Suspected Invasive Pneumococcal Disease in Australia

This study provides a quantitative estimate of the total burden of invasive pneumococcal disease preventable by vaccination programs in Australia

Research

The pervasive effects of timing of parental mental health disorders on adolescent deliberate self-harm risk

This study shows that timing is important for understanding intergenerational transmission of deliberate self-harm risk

Research

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas

The outcome for children with high-grade gliomas (HGG) remains dismal, with a 2-year survival rate of only 10% to 30%.

Research

Measuring early child development in low and middle income countries: Investigating the validity of the early Human Capability Index

Inclusion of early child development in the United Nations Sustainable Development Agenda raises issues of how this goal should be monitored, particularly in low resource settings. The aim of this paper was to explore the validity of the early Human Capability Index (eHCI); a population measure designed to capture the holistic development of children aged 3-5 years. Convergent, divergent, discriminant and concurrent validity were examined by exploring the associations between eHCI domains and child (sex, age, stunting status, preschool attendance) and family (maternal education, home learning environment) characteristics. Analyses were repeated using data from seven low and middle income countries.

Research

Exploration of the Performance of a Hybrid Closed Loop Insulin Delivery Algorithm That Includes Insulin Delivery Limits Designed to Protect Against Hypoglycemia

The algorithm that was tested against moderate exercise and an overreading glucose sensor performed well in terms of hypoglycemia avoidance

Research

Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells

This study assessed an alternative approach, using a small scale halide assay that can be adapted for a personalized high throughput setting to analyze CFTR function of pAEC.

Research

Early childhood development of boys with genital anomalies

We found no increased risk of poor development among boys with hypospadias or undescended testis

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High burden of RSV hospitalization in very young children: a data linkage study

RSV was associated with substantial burden of childhood hospitalization specifically in children aged <3 months and in Indigenous children and pre-term children

Research

Gene polymorphisms, breast-feeding, and development of food sensitization in early childhood

The effect of breast-feeding on the development of allergic disease is uncertain