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Research
Short-term changes in frequencies of circulating leukocytes associated with narrowband UVB phototherapy in people with clinically isolated syndromeSince B cells are increasingly targeted by MS therapies, the effects of narrowband UVB phototherapy in people with MS should be investigated further
Research
Declining transition rates to psychotic disorder in "ultra-high risk" clients: Investigation of a dilution effectLater ultra-high risk psychosis cohorts presented with different clinical intake characteristics than earlier cohorts
Research
Two females with mutations in USP9X highlight the variable expressivity of the intellectual disability syndromeThe genetic causes of intellectual disability (ID) are heterogeneous and include both chromosomal and monogenic etiologies.
Research
Vector fields of risk: A new approach to the geographical representation of childhood asthmaOne of the major challenges in health studies with a spatial dimension is to produce valid and meaningful geographical representations of risk.
News & Events
Oscar Hogan - How my brother living with T1D influenced my careerWe spoke to Oscar and asked him to share his story about the challenges he faces when trying to support his brother, joining the Centre as a student and what T1D research means to him, his brother and his family.
News & Events
Crippa's Footy ClinicDiabetes Research Western Australia (DRWA) are inviting children aged 6-16 living with type 1 and type 2 diabetes to join West Coast Eagles forward Jamie Cripps for a fun-filled footy clinic.
News & Events
Should I send my child to school?With Term 2 commencing this week, many parents are unsure as to whether to send their child with type 1 diabetes back to school. To assist parents with their own decision-making process, it is important to consider the individual risks and benefits for each family.
Research
"i Think i Could Have Used It Better": Experiences of Youth with High HbA1c Commencing Advanced Hybrid Closed-Loop Therapy in a Clinical Trial Setting - A Qualitative ResearchAdvanced hybrid closed-loop (AHCL) therapy improves glycemia. However, it is not known if there is an improvement in overall outcomes with AHCL for youth with type 1 diabetes (T1D) at high risk of diabetes-related complications. The study aimed to capture the experiences of youth with suboptimal glycemic control when commencing AHCL therapy in a clinical trial setting.
Research
Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive CombinationsAntibodies that target immune checkpoints such as cytotoxic T lymphocyte antigen 4 (CTLA‐4) and the programmed cell death protein 1/ligand 1 (PD-1/PD-L1) are now a treatment option for multiple cancer types. However, as a monotherapy, objective responses only occur in a minority of patients. Chemotherapy is widely used in combination with immune checkpoint blockade (ICB). Although a variety of isolated immunostimulatory effects have been reported for several classes of chemotherapeutics, it is unclear which chemotherapeutics provide the most benefit when combined with ICB.
Research
Hand function development of children with hemiplegic cerebral palsy: A scoping reviewHemiplegic cerebral palsy (hCP) typically impacts sensorimotor control of the hand, but comprehensive assessments of the hands of children with hCP are relatively rare. This scoping review summarizes the development of hand function for children with hCP.