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Research

Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity

Environmental factors including excessive caloric intake lead to disordered lipid metabolism and fatty liver disease.

Research

Trough concentrations of vancomycin: Adult therapeutic targets are not appropriate for Children

Despite the need for effective vancomycin therapy, there are few data guiding vancomycin monitoring in children. We reviewed retrospectively vancomycin use...

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Umbilical venous blood flow and its measurement in the human fetus

In this review, we evaluate the published methodologies to describe a noninvasive technique for the quantitative assessment of umbilical venous blood flow in...

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Updated model of group A Streptococcus M proteins based on a comprehensive worldwide study

Group A Streptococcus (GAS) M protein is an important virulence factor and potential vaccine antigen, and constitutes the basis for strain typing (emm-typing).

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Maternal vitamin D levels during pregnancy and offspring eating disorder risk in adolescence

This is the first study to link low gestational vitamin D to increased eating disorder risk in female offspring of Caucasian mothers.

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A "Candidate-Interactome" Aggregate Analysis of Genome-Wide Association Data in Multiple Sclerosis

The interaction between genotype and Epstein Barr virus emerges as relevant for multiple sclerosis etiology.

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Associations between Handedness and Cerebral Lateralisation for Language: A Comparison of Three Measures in Children

It has been suggested that quantitative measures of differential hand skill or reaching preference may provide more valid measures than traditional...

Research

Alternative Recruitment Strategies Influence Saliva Sample Return Rates in Community-Based Genetic Association Studies

Using data from three large-scale genetic association studies we compared recruitment strategy and sample return rates.

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Familial aggregation of childhood and adult cancer in the Utah genealogy

We explored familial aggregation of cancer in a population-based case-control study using genealogical record linkage and designed to overcome limitations of...

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Socioeconomic Status Accounts for Rapidly Increasing Geographic Variation in the Incidence of Poor Fetal Growth

This study assessed the temporal stability of spatial patterns in the incidence of preterm and small-for-gestational-age (SGA) in regional Western Australia,...