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Chronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear

The introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...

Asthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable...

In healthy individuals, deep inspiration produces bronchodilation and reduced airway responsiveness, which may be a response of the airway wall to mechanical...

The aim of our study was to determine the contribution of secular trends and sample size to lung function reference equations, and establish the number...

An improved understanding of the roles of protein kinases in intracellular signalling and disease progression has driven significant advances in protein...

The expression pattern of FcεRI on DC and basophils differentiates asthmatic from non-asthmatic atopic children

These findings suggest the utility of specific FOT outcomes is dependent on the respiratory disease being assessed

Type 1 and 3 interferon response capacity appears strongly developmentally constrained at birth

Here, we review the basic concepts in bioinformatics and genomic data analysis and illustrate the application of these tools to further our understanding of lung diseases