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High Vitamin D-Binding Protein Concentration, Low Albumin, and Mode of Remission Predict Relapse in Crohn's DiseaseAssociations between Vitamin D-binding protein, serum Vitamin D, and the calculated free Vitamin D concentrations with the risk of Crohn's disease flare
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Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16Though HRVs are usually innocuous viruses, they can trigger serious consequences in certain individuals, especially in the setting of IFN synthesis.
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Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptomsPregnancy is a time of vulnerability for vitamin D insufficiency, and there is an emerging literature associating low levels of 25(OH)-vitamin D with...
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The effects of in utero vitamin D deficiency on airway smooth muscle mass and lung functionIn this study, we aimed to uncover the molecular mechanisms contributing to altered lung structure and function.
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Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive DevelopmentNew research links poor language to lack of Vitamin D in womb.
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Circulating Memory B Cells in Early Multiple Sclerosis Exhibit Increased IgA+ Cells, Globally Decreased BAFF-R Expression and an EBV-Related IgM+ Cell SignatureMultiple sclerosis (MS) is an immune-mediated inflammatory disease of the central nervous system that results in demyelination of axons, inefficient signal transmission and reduced muscular mobility. Recent findings suggest that B cells play a significant role in disease development and pathology. To further explore this, B cell profiles in peripheral blood from 28 treatment-naive patients with early MS were assessed using flow cytometry and compared to 17 healthy controls.
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Developing an Online Tool to Promote Safe Sun Behaviors With Young Teenagers as Co-researchersDespite education about the risks of excessive sun exposure, teenagers in Australia are sun-seeking, with sunburn common in summer. Conversely, some regular (time-limited) exposure to sunlight (that avoids sunburn) is necessary for vitamin D and healthy bones and other molecules important for immune and metabolic health. New interventions are thus required to better support teenagers to make healthy and balanced decisions about their sun behaviors.
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Short-term changes in frequencies of circulating leukocytes associated with narrowband UVB phototherapy in people with clinically isolated syndromeSince B cells are increasingly targeted by MS therapies, the effects of narrowband UVB phototherapy in people with MS should be investigated further
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Cellular and molecular mechanisms of vitamin D in food allergyEpidemiological evidence from the past decade suggests a role of vitamin D in food allergy pathogenesis
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Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrityIn disease settings, vitamin D may be important for maintaining optimal lung epithelial integrity and suppressing inflammation, but less is known of its effects prior to disease onset.