Injection of BM-differentiated DCs from nonchimeric mice restored the reduced immune responses of PGE2-chimeric mice.
In this chapter, evidence for and evidence against the involvement of vitamin D in the immunoregulatory properties of UV radiation is presented.
The analysis of 25-hydroxyvitamin D3 (25(OH)D3) and related metabolites represents a considerable challenge for both clinical and research laboratori…
Ultraviolet radiation (UVR) from sunlight is immunomodulatory and the main source of vitamin D for humans.
Vitamin D is synthesised by ultraviolet (UV) irradiation of skin and is hypothesized to be a direct mediator.
Inflammatory mediators from peripheral tissues may control dendritic cell (DC) development in the bone marrow.
In this study, using a mouse model, we determined whether vitamin D deficiency in utero and during early life modulated the severity of asthma.
Exposure of skin to UV radiation (UVR) prior to allergen exposure can inhibit inflammatory airways disease in mice by reducing effector CD4+ T cells…
Humans obtain most of their vitamin D through the exposure of skin to sunlight
The prevalence of vitamin D deficiency is increasing and has been linked to obstructive lung diseases including asthma and chronic obstructive pulmon…