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Researchers find new way to deliver ‘smart drugs’ for hard-to-treat diseasesResearchers from Perth’s The Kids Research Institute Australia have developed a world-first screening tool that helps deliver smart drugs into cells to battle hard-to-treat diseases like cancer and Duchenne Muscular Dystrophy.
Research
Effect of Fluoxetine on Obsessive-Compulsive Behaviors in Children and Adolescents With Autism Spectrum Disorders: A Randomized Clinical TrialTreatment with fluoxetine compared with placebo resulted in significantly lower scores for obsessive-compulsive behaviors at 16 weeks
Research
Discrete choice experiment to evaluate preferences of patients with cystic fibrosis among alternative treatment-related health outcomes: A protocolThe aim of this study is to identify and quantify the preferences of patients with cystic fibrosis regarding treatment outcomes
Research
“Sometimes Our Mob Don't Really Take It Serious Until It's Serious”: The Experiences of Western Australian Aboriginal Adolescents Living With Type 2 Diabetes, Their Parents, and Their Family MembersIn Australia, Aboriginal children experience disproportionate rates of type 2 diabetes (T2D) compared with non-Aboriginal children. The aim of this qualitative study was to explore the experiences of Aboriginal adolescents with T2D and their family members to better understand the influences of T2D on self-management, with findings used to inform an enhanced service model of care.
Research
Evaluation of safety and immunogenicity of a group a streptococcus vaccine candidate (mj8vax) in a randomized clinical trialIntramuscular administration of novel acetylated peptide-protein conjugate vaccine candidate MJ8VAX was demonstrated to be safe and immunogenic
Research
Social impairments in autism spectrum disorder are related to maternal immune history profilethis study is the first to show an association between immune activation history in the mother and increased ASD symptom severity in children with ASD
Research
Does perinatal exposure to exogenous oxytocin influence child behavioural problems and autistic-like behaviours to 20 years of ageThis study is the first to investigate longitudinal mental health outcomes associated with the use of oxytocin-based medications during labour
Research
The rationale for action to end new cases of rheumatic heart disease in AustraliaThe choice of RHD is telling: the disease is a marker of inequality, a novel lens for considering health systems and a feasible target for disease control.
Research
Developmental trajectories of sleep problems from childhood to adolescence both predict and are predicted by emotional and behavioral problemsFindings from this study provide empirical evidence for the heterogeneity of sleep problems and their development
Research
Polygenic risk of ischemic stroke is associated with cognitive abilityFindings from this study indicate that even in the absence of stroke, being at high polygenic risk of ischemic stroke is associated with lower cognitive ability