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Showing results for "early lung health"
Research
Evaluating the effectiveness of the Play Active policy intervention and implementation support in early childhood education and care: a pragmatic cluster randomised trial protocolDaily physical activity is critical during the early years of life for facilitating children's health and development. A large proportion of preschool children do not achieve the recommended 3 h of daily physical activity. Early childhood education and care (ECEC) services are a key setting to intervene to increase physical activity. There is a significant need for ECEC specific physical activity policy, including clearer guidelines on the amount of physical activity children should do during care, and strategies for implementation of these guidelines.
Research
Immunogenicity, reactogenicity, and IgE-mediated immune responses of a mixed whole-cell and acellular pertussis vaccine schedule in Australian infants: A randomised, double-blind, noninferiority trialIn many countries, infant vaccination with acellular pertussis (aP) vaccines has replaced use of more reactogenic whole-cell pertussis (wP) vaccines. Based on immunological and epidemiological evidence, we hypothesised that substituting the first aP dose in the routine vaccination schedule with wP vaccine might protect against IgE-mediated food allergy. We aimed to compare reactogenicity, immunogenicity, and IgE-mediated responses of a mixed wP/aP primary schedule versus the standard aP-only schedule.
News & Events
People power takes tiny study to the next levelOne of the biggest problems facing young people with neuromuscular disorders is the risk of breathing problems caused by muscle weakness during sleep.
News & Events
Support for kids’ mental health and new cancer therapies boosted by WA Child Research FundThe Kids Research Institute Australia researchers have been awarded 12 grants in the latest round of funding from the WA Child Health Research Fund (formerly the Telethon-Perth Children’s Hospital Research Fund).
News & Events
Raine Foundation grants to support key child health researchThree outstanding young researchers from The Kids Research Institute Australia have been named Raine Fellows and received valuable Raine Priming Grants to support their child health research.
News & Events
National Asthma Week: 10 things you need to know about asthmaAsthma affects about half a million Australian children and is one of the most common reasons why kids need to see a doctor or go to emergency.
News & Events
NHMRC Fellowships awarded to support child health researchSeven leading The Kids Research Institute Australia researchers have been awarded Fellowships from the National Health and Medical Research Council (NHMRC).
Research
Pneumococcal conjugate vaccination at birth in a high-risk setting: No evidence for neonatal T-cell toleranceConcerns about the risk of inducing immune deviation-associated "neonatal tolerance" as described in mice have restricted the widespread adoption...
Research
Early treatment with fluvoxamine, bromhexine, cyproheptadine, and niclosamide to prevent clinical deterioration in patients with symptomatic COVID-19: a randomized clinical trialRepurposed drugs with host-directed antiviral and immunomodulatory properties have shown promise in the treatment of COVID-19, but few trials have studied combinations of these agents. The aim of this trial was to assess the effectiveness of affordable, widely available, repurposed drugs used in combination for treatment of COVID-19, which may be particularly relevant to low-resource countries.
Research
Nasal Delivery of Haemophilus haemolyticus Is Safe, Reduces Influenza Severity, and Prevents Development of Otitis Media in MiceDespite vaccination, influenza and otitis media (OM) remain leading causes of illness. We previously found that the human respiratory commensal Haemophilus haemolyticus prevents bacterial infection in vitro and that the related murine commensal Muribacter muris delays OM development in mice. The observation that M muris pretreatment reduced lung influenza titer and inflammation suggests that these bacteria could be exploited for protection against influenza/OM.