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CFTR-dependent defect in alternatively-activated macrophages in cystic fibrosisCFTR-dependent imbalance of macrophage phenotypes and functions could contribute to the exaggerated inflammatory response seen in CF lung disease
Research
The correlation between central and peripheral oxytocin concentrations: A systematic review and meta-analysisThese results indicate a coordination of central and peripheral oxytocin release after stress and after intranasal administration
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A longitudinal analysis of the influence of the neighborhood environment on recreational walking within the neighborhood: Results from RESIDEevidence of the positive impact of well-connected neighborhoods and access to local parks of varying sizes on local residents’ recreational walking and health
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Long-term employment among people at ultra-high risk for psychosisWe sought to investigate the long-term unemployment rate and baseline predictors of employment status at follow-up in a large ultra-high risk cohort.
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Two females with mutations in USP9X highlight the variable expressivity of the intellectual disability syndromeThe genetic causes of intellectual disability (ID) are heterogeneous and include both chromosomal and monogenic etiologies.
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Prevalence and treatment of psychiatric disorders other than psychosis in children and adolescents with 22q11DS: Examining associations with social and role functioningThe aim of this study was to investigate the prevalence and treatment of non-psychotic psychiatric disorders
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Environment Changes Genetic Effects on Respiratory Conditions and Allergic PhenotypesGenotype-phenotype associations relating to bronchitis and allergy susceptibility are dependent on the environment
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Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrityIn disease settings, vitamin D may be important for maintaining optimal lung epithelial integrity and suppressing inflammation, but less is known of its effects prior to disease onset.
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Evidence of functional cell-mediated immune responses to nontypeable Haemophilus influenzae in otitis-prone childrenThese data provide evidence that otitis-prone children do not have impaired functional cell mediated immunity
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Duration of general anaesthetic exposure in early childhood and long-term language and cognitive abilityAnaesthetic dose causing toxicity in animals has been evaluated, but the relationship between duration of VA exposure and development in children remains vague.