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Research

The time lag prior to the rise in glucose requirements to maintain stable glycaemia during moderate exercise in a fasted insulinaemic state is of short duration

There is a 20-min low exogenous glucose demand period during which the glucose requirements to maintain stable glycaemia do not increase during moderate exercise

Research

Access to health professionals by children and adolescents with mental disorders: Are we meeting their needs?

The typical number of visits to health professionals by children with mental disorders during a 12-month period is relatively small

Research

Increasing diversity within the Global Lung Function Initiative

The Global Lung Function Initiative has worked to develop all‐age, multi‐ethnic reference equations for the major clinical lung function tests

Research

Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice

Skin exposure to ultraviolet radiation alters the faecal microbiome, and further investigations to explore the implications of this in health and disease are warranted

Research

Discovering the sense of touch: Protocol for a randomised controlled trial examining the efficacy of a intervention for children with cerebral palsy

This study will assess the efficacy of an intervention to increase somatosensory discrimination ability in children with cerebral palsy

Research

A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery

This report thus establishes a discovery platform for identifying novel, functional CPPs to expand the delivery landscape of druggable intracellular targets for biological therapeutics

Research

Clinical development strategy for a candidate group A streptococcal vaccine

This review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin

Research

The role of PKCzeta in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil

Here, we present evidence that there are two major control points to explain the immunodeficiency in CB T-cells, leading to a decreased IFNy synthesis.

Research

Pulmonary delivery of virosome-bound antigen enhances antigen-specific CD4+ T cell proliferation compared to liposome-bound or soluble antigen

Pulmonary administration of biomimetic nanoparticles loaded with antigen may represent an effective strategy to directly modulate adaptive immune responses