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Research
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015Globally, life expectancy from birth increased from 61·7 years in 1980 to 71·8 years in 2015
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A Cost-Effectiveness Analysis of Sensor-Augmented Insulin Pump Therapy and Automated Insulin Suspension versus Standard Pump TherapyA clinical trial-based economic evaluation was performed in which the net costs and effectiveness of the two treatment modalities were calculated and...
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Advances in Automated Insulin Delivery with the Medtronic 780G: The Australian ExperienceTo assess the real-world performance of MiniMed™ 780G for Australians with type 1 diabetes (T1D) following advanced hybrid closed loop (AHCL) activation and to evaluate the effect of changing from MiniMed 670/770G to 780G.
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Copeptin Kinetics and Its Relationship to Osmolality During Rehydration for Diabetic Ketoacidosis in ChildrenCopeptin is a surrogate marker for arginine vasopressin (AVP) release in response to hyperosmolal stimuli such as diabetic ketoacidosis (DKA). The objective of this work is to characterize kinetics of copeptin and osmolality, and their dynamic relationship during rehydration and insulin therapy in children with type 1 diabetes (T1D) and DKA.
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Nitrous oxide (N2O) and subsequent open-label SSRI treatment of adolescents with depression (NOTAD): Study protocol for a randomised controlled trialThe aim of this study is to investigate the antidepressant effects of N2O and N2O and SSRI combined.
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Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative studyThe objective of this study was to compare international trends in pre-eclampsia rates and in overall pregnancy hypertension rates...
A world-first study led by Dr Aveni Haynes at The Kids’ Rio Tinto Children’s Diabetes Centre, is helping to detect early changes in blood sugar levels.
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ABCA3 lung disease in an ex 27 week preterm infant responsive to systemic glucocorticosteroidsThis is a case of ABCA3 lung disease that demonstrated improvement after systemic glucocorticosteroid administration
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Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8+ T Cell ResponsesMany proteasomes expressed by normal cells and cells exposed to cytokines are "mixed", that is, contain both standard and immunoproteasome subunits.
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Trough concentrations of vancomycin: Adult therapeutic targets are not appropriate for ChildrenDespite the need for effective vancomycin therapy, there are few data guiding vancomycin monitoring in children. We reviewed retrospectively vancomycin use...