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Research

The histone demethylase dLsd1 regulates organ size by silencing transposable elements

The specific role of chromatin modifying factors in the timely execution of transcriptional changes in gene expression to regulate organ size remains largely unknown. Here, we report that in Drosophila melanogaster depletion of the histone demethylase dLsd1 results in the reduction of wing size. dLsd1 depletion affects cell proliferation and causes an increase in DNA damage and cell death.

Research

Bringing optimised COVID-19 vaccine schedules to immunocompromised populations: statistical elements and design

Bringing optimised coronavirus disease 2019 (COVID-19) vaccine schedules to immunocompromised populations (BOOST-IC) is a multi-site, adaptive platform trial designed to assess the effect of different booster vaccination schedules in the Australian immunocompromised population on the immunogenicity, safety and cross-protection against COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants. 

Research

Parainfluenza Virus Infection in an Australian Community-based Birth Cohort

In a community-based birth cohort of 158 Australian infants followed to age 2 years, the incidence rate of human parainfluenza virus (HPIV) was 0.42 (95% CI = 0.33, 0.54) episodes per child-year with episodes occurring year-round, peaking in the spring season.

Research

Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy

Slightly less than 1 h of general anaesthesia in early infancy does not alter neurodevelopmental outcome at age 5 years

Honours and Masters Scholarship

Applications are open for our 2025 Honours and Masters Scholarships with the purpose of providing funding for students to develop and support their type 1 diabetes (T1D) related research.

News & Events

New school year

Good planning and communication between families and schools is very important to ensure children are safe and supported. With the new school year underway, hear from our Social Work team with their top tips on managing the start of a new school year.

News & Events

Diabetes Nutrition Videos

What is a Carboyhdrate - Diabetes Nutrition Video We know there is a lot of information out there about food and nutrition and that parents want to

News & Events

Meet Lucy

Learn about Lucy's journey through the eyes of her mum, and through the video "T1D: Our Lucy".

Theme Leads

Read about the Research Focus Area Leads at the Children's Diabetes Centre.

News & Events

Self-efficacy groups 2020

Perth Children’s Hospital’s Diabetes Service has released the dates for its self-efficacy groups for 2020.