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Research
Dysregulated IL-1β-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by HydroxychloroquineWe propose that hydroxychloroquine could be repurposed to reduce the risk of rheumatic heart disease after acute rheumatic fever
Research
Community-based participatory action research on rheumatic heart disease in an Australian Aboriginal homeland: Evaluation of the ‘On track watch’ projectBased in 'both-way learning', the aim of this study was to co-design, implement and evaluate community-based participatory action research to achieve this vision
Research
High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin G injections in Ethiopian children and adults with rheumatic heart diseaseIntramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary prophylaxis to prevent acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Uncertainties regarding inter-ethnic and preparation variability, and target exposure profiles of BPG injection are key knowledge gaps for RHD control.
Research
Understanding group A streptococcal pharyngitis and skin infections as causes of rheumatic fever: Protocol for a prospective disease incidence studyThis study will identify the incidence of true Group A Streptococcal pharyngitis and serological responses to Group A Streptococcal GAS skin infections
Research
Prospective cohort study of childhood behaviour problems and adolescent sexual risk-taking: Gender mattersThis study sought to determine relationships, by gender, between childhood behaviour problems and adolescent risky sexual behaviours and substance use.
Research
Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic feverA sample target product profile for reformulated benzathine penicillin G is presented
Research
Focused cardiac ultrasound screening for rheumatic heart disease by briefly trained health workers: A study of diagnostic accuracyEchocardiographic screening for rheumatic heart disease (RHD) can identify individuals with subclinical disease who could benefit from antibiotic prophylaxis.
Research
Seven key actions to eradicate rheumatic heart disease in Africa: the Addis Ababa communiquéDevelop a 'roadmap' of key actions that need to be taken by governments to eliminate ARF and eradicate RHD in Africa
News & Events
The Kids researchers granted $5 million to prevent RHD across PacificA team led by Dr Joseph Kado from the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, and The University of Western Australia (UWA) has been awarded $5 million by the Federal Government in a major push to prevent rheumatic heart disease across the Pacific.
News & Events
Call for urgent funding boost for RHD in AustraliaThere are calls for a significant and urgent injection of $40 million in funding to tackle Rheumatic Heart Disease (RHD) following Monday night’s Four Corners episode.