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Epidemiological studies have demonstrated that survivors of acute burn trauma are at long-term increased risk of developing a range of morbidities. The mechanisms underlying this increased risk remain unknown. This study aimed to determine whether burn injury leads to sustained immune dysfunction that may underpin long-term morbidity. Plasma and peripheral blood mononuclear cells were collected from 36 pediatric burn survivors >3 years after a non-severe burn injury (<10% total body surface area) and from age/sex-matched non-injured controls.
Early infancy oral vitamin D supplementation does not appear to reduce the development of early childhood allergic disease
To our knowledge, this is the first study to show that the reported 25(OH)D concentration may be influenced by both age and assay type
As the prevalence of allergic disease dramatically rises worldwide, prevention strategies are increasingly being considered.
Increased maternal egg ingestion is associated with increased breastmilk ovalbumin, and markers of immune tolerance in infants
There is significant data to support the hypothesis that early life nutrition in the fetus, infant and young child can have profound effects on long-term health
Vitamin D deficiency in a predominantly white Caucasian cohort of pregnant women is less prevalent than has been reported in other studies
This paper discusses the rising prevalence of allergic disease in children. This review article considers recent findings in the field of paediatric immune...
This review article examines the evidence of the impact of in utero and postnatal vitamin D exposure on allergy risk in childhood
Reliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also...